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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
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Seattle WA 98121
Phone:
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Leptin

Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Gene Name: Leptin
Synonyms: LEP, Leptin, LEPD, Obese protein, Obese, mouse, homolog of, Obesity factor, OBS, OB
Target Sequences: NM_000230 NP_000221.1 P41159

Publications (3)

1
Leptin as a potential target for estrogen receptor-positive breast cancer. Yom CK, Lee KM, Han W, Kim SW, Kim HS, Moon BI, Jeong KY, Im SA, Noh DY. Journal of breast cancer. 2013 16:138-45. (WB; Human) [Full Text Article] [PubMed:23843844] [PMC:PMC3706857] Related Antibodies: LS-C25172.
2
Hypoplastic left heart syndrome is associated with structural and vascular placental abnormalities and leptin dysregulation. Jones HN, Olbrych SK, Smith KL, Cnota JF, Habli M, Ramos-Gonzales O, Owens KJ, Hinton AC, Polzin WJ, Muglia LJ, Hinton RB. Placenta. 2015 36:1078-86. (WB; Mouse) [Full Text Article] [PubMed:26278057] Related Antibodies: LS-B1459.
3
Delta-like protein 1 in the pituitary-adipose axis in the adult male mouse. Bello AR, Puertas-Avendaño RA, González-Gómez MJ, González-Gómez M, Laborda J, Damas C, Ruiz-Hidalgo M, Diaz C. Journal of neuroendocrinology. 2017 August;29: [Full Text Article] [PubMed:28718206] [PMC:PMC6084355]

☰ Filters
Antibodies (206)
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Leptin (354)
Human (135)
Mouse (78)
Rat (67)
Bovine (28)
Chicken (10)
Chimpanzee (6)
Cow (16)
Dog (11)
Gibbon (6)
Goat (4)
Guinea pig (1)
Hamster (9)
Horse (18)
Macaque (2)
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rabbit (141)
mouse (39)
goat (15)
chicken (2)
rat (8)
sheep (1)
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monoclonal mc (47)
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AT7E10 (1)
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C4 (8)
LEP-02 (1)
YD-HLEP4B6 (1)
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aa22-167 (35)
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Leptin Antibody - Anti-LEP / Leptin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Leptin Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$425
Leptin Antibody - Human, Kidney:Formalin-Fixed Paraffin-Embedded (FFPE)
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Leptin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
500 µg/$425
Leptin Antibody - Anti-LEP / Leptin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Leptin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Hamster, Horse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Leptin Antibody - Anti-LEP / Leptin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Leptin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Sheep, Bovine, Mouse, Goat, Dog, Rat, Hamster, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Leptin Antibody - Detection limit for recombinant GST tagged LEP is approximately 0.1 ng/ml as a capture antibody.
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Leptin Mouse anti-Human Monoclonal (3G1-1C9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$365
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Leptin Rabbit anti-Human Polyclonal (aa8-37) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$740
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Leptin Rabbit anti-Human Polyclonal (aa8-37) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$740
Leptin Antibody - Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Leptin Goat anti-Rat Polyclonal Antibody
Rat
ELISA, WB
Unconjugated
50 µg/$285; 100 µg/$325
Leptin Antibody - Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Leptin Goat anti-Rat Polyclonal (Biotin) Antibody
Rat
ELISA, WB
Biotin Conjugated
25 µg/$285; 50 µg/$325
Leptin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$530
Leptin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Bovine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$850
Leptin ELISA Kit
Select
Sandwich
96-Well Microplate
Pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$580
Leptin ELISA Kit
Select
Sandwich
96-Well Microplate
Human
1.638 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$470
Leptin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$810
Leptin Antibody - Western Blot (non-reducing) of Leptin antibody
Select
Leptin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$285; 100 µg/$325
Leptin Antibody - Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Leptin Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$285; 100 µg/$325
Leptin ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
4.096 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$470
Select
Leptin Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
250 µg/$455
Leptin Antibody - LEP Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Leptin Rabbit anti-Human Polyclonal (aa8-37) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$325
Leptin Antibody - Western blot of recombinant Leptin.
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Leptin Rabbit anti-Cow Polyclonal (aa29-160) Antibody
Bovine, Cow
WB
Unconjugated
100 µl/$265; 200 µl/$315; 500 µl/$465; 1 ml/$560
Leptin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Saliva, Serum, Tissue Homogenates
1 Plate/$540
Leptin ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
10.97 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$470
Leptin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$650
Leptin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Horse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$870
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E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
16.0 kDa
200 µg/$215; 1 mg/$285
Viewing 1-25 of 354 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).