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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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Leptin

Leptin is a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.

Gene Name: Leptin
Synonyms: LEP, Leptin, LEPD, Obese protein, Obese, mouse, homolog of, Obesity factor, OBS, OB
Target Sequences: NM_000230 NP_000221.1 P41159

Publications (3)

1
Leptin as a potential target for estrogen receptor-positive breast cancer. Yom CK, Lee KM, Han W, Kim SW, Kim HS, Moon BI, Jeong KY, Im SA, Noh DY. Journal of breast cancer. 2013 16:138-45. (WB; Human) [Full Text Article] [PubMed:23843844] [PMC:PMC3706857] Related Antibodies: LS-C25172.
2
Hypoplastic left heart syndrome is associated with structural and vascular placental abnormalities and leptin dysregulation. Jones HN, Olbrych SK, Smith KL, Cnota JF, Habli M, Ramos-Gonzales O, Owens KJ, Hinton AC, Polzin WJ, Muglia LJ, Hinton RB. Placenta. 2015 36:1078-86. (WB; Mouse) [Full Text Article] [PubMed:26278057] Related Antibodies: LS-B1459.
3
Delta-like protein 1 in the pituitary-adipose axis in the adult male mouse. Bello AR, Puertas-Avendaño RA, González-Gómez MJ, González-Gómez M, Laborda J, Damas C, Ruiz-Hidalgo M, Diaz C. Journal of neuroendocrinology. 2017 August;29: [Full Text Article] [PubMed:28718206] [PMC:PMC6084355]


Leptin Antibody - Anti-LEP / Leptin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
Rabbit Polyclonal to Mouse Leptin
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$425
Leptin Antibody - Human, Kidney:Formalin-Fixed Paraffin-Embedded (FFPE)
Select
Mouse Monoclonal (IgG1,k) to Human Leptin
Human
ELISA, IHC, IHC-P, WB
Unconjugated
500 µg/$425
Leptin Antibody - Anti-LEP / Leptin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human Leptin
Rabbit, Mouse, Dog, Bovine, Hamster, Horse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Leptin Antibody - Anti-LEP / Leptin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human Leptin
Chicken, Sheep, Bovine, Mouse, Goat, Dog, Rat, Hamster, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$485
Leptin Antibody - Detection limit for recombinant GST tagged LEP is approximately 0.1 ng/ml as a capture antibody.
Select
Mouse Monoclonal [clone 3G1-1C9] (IgG2b,k) to Human Leptin
Human
ELISA, WB
Unconjugated
100 µg/$365
Select
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$590
Select
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$740
Select
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$740
Select
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$740
Select
Rabbit Polyclonal (IgG) to Human Leptin
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$740
Leptin Antibody - Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Goat Polyclonal to Rat Leptin
Rat
ELISA, WB
Unconjugated
50 µg/$285; 100 µg/$325
Leptin Antibody - Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Goat Polyclonal to Rat Leptin
Rat
ELISA, WB
Biotin Conjugated
25 µg/$285; 50 µg/$325
Leptin Antibody - Western Blot (non-reducing) of Leptin antibody
Select
Rabbit Polyclonal to Human Leptin
Human
ELISA, WB
Unconjugated
50 µg/$285; 100 µg/$325
Leptin Antibody - Western Blot (non-reducing) of Leptin antibody. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse Leptin
Mouse
ELISA, WB
Unconjugated
50 µg/$285; 100 µg/$325
Select
Rabbit Polyclonal (IgG) to Human Leptin
Human
WB
Unconjugated
250 µg/$455
Leptin Antibody - LEP Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human placenta tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Select
Rabbit Polyclonal to Human Leptin
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$325
Leptin Antibody - Western blot of recombinant Leptin.
Select
Rabbit Polyclonal to Cow Leptin
Bovine, Cow
WB
Unconjugated
100 µl/$265; 200 µl/$315; 500 µl/$465; 1 ml/$560
Select
Rabbit Polyclonal to Human Leptin
Mouse, Rat, Pig, Human, Monkey
ELISA, IP, RIA, WB
Unconjugated
100 µl/$545
Select
Mouse Monoclonal [clone YD-HLEP4B6] (IgG1) to Human Leptin
Human
ELISA, IP, WB
Unconjugated
500 µg/$515; 1 mg/$755
Leptin Antibody - Confocal immunofluorescence of Leptin (LEP) Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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Rabbit Polyclonal to Human Leptin
Human
IF, WB
Unconjugated
400 µl/$325
Leptin Antibody - Leptin antibody Western blot. All lanes: Anti LEP/leptin at 0.5 ug/ml. WB: NIH3T3 Whole Cell Lysate at 40 ug. Predicted band size: 16 kD. Observed band size: 16 kD.
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Rabbit Polyclonal to Mouse Leptin
Mouse
ELISA, WB
Unconjugated
100 µg/$325
Leptin Antibody - Immunohistochemistry analysis of Ob antibody in paraffin-embedded human breast carcinoma tissue.
Select
Rabbit Polyclonal (IgG) to Human Leptin
Mouse, Rat, Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$265; 100 µl/$325
Leptin Antibody - Western Blot; Sample: Recombinant LEP, Mouse.
Select
Rat Monoclonal [clone C4] (IgG) to Mouse Leptin
Mouse
WB
Unconjugated
100 µl/$255; 200 µl/$295; 500 µl/$435; 1 ml/$515
Select
Mouse Monoclonal [clone 4F12] (IgG1) to Human Leptin
Human
ELISA
Unconjugated
0.2 mg/$515; 0.5 mg/$725
Leptin Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human Leptin
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$325; 200 µl/$375
Viewing 1-25 of 206 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).