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RXFP2 / LGR8

relaxin/insulin-like family peptide receptor 2

Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). LGR8 is a member of the Relaxin Receptor subfamily. LGR8 has been shown to be important for testis descent.

Gene Name: relaxin/insulin-like family peptide receptor 2
Family/Subfamily: GPCR , Relaxin
Synonyms: RXFP2, G-protein coupled receptor 106, GPR106, INSL3R, LGR8, GREAT, Relaxin receptor 2, LGR8.1, RXFPR2
Target Sequences: NM_130806 NP_570718.1 Q8WXD0

☰ Filters
Antibodies (33)
Proteins (2)
Over-Expression Lysate (2)
Primary (33)
RXFP2 / LGR8 (35)
Human (33)
Mouse (15)
Rat (7)
Bovine (3)
Chimpanzee (3)
Dog (3)
Guinea pig (3)
Horse (4)
Monkey (1)
IHC (5)
IHC-Fr (1)
IHC-P (7)
WB (24)
Flo (2)
ELISA (11)
ICC (2)
IF (3)
Peptide-ELISA (3)
rabbit (33)
Product Group
GPCR Database Antibodies (4)
IHCPlus (3)
PathPlus Cancer (2)
IgG (23)
polyclonal pc (33)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (22)
aa692-721 (7)
aa653-702 (4)
C-Terminus (2)
Cytoplasmic Domain (2)
90-170 aa, Internal (1)
Extracellular Domain (1)
Internal (1)
aa103-152 (1)
aa113-162 (1)
aa737-754 (1)
No (32)
Yes (3)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
RXFP2 / LGR8 Antibody - Anti-RXFP2 / LGR8 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
RXFP2 / LGR8 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µg/$460
RXFP2 / LGR8 Antibody - Anti-RXFP2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µg/$460
RXFP2 / LGR8 Antibody - Anti-RXFP2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µg/$440
RXFP2 / LGR8 Antibody - Brain, Glioblastoma
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Cancer
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Mouse, Horse, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$440
RXFP2 / LGR8 Antibody - Western blot of Relaxin Receptor 2 antibody
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (90-170 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
RXFP2 / LGR8 Antibody - Western blot analysis of GPCR LGR8 using anti-GPCR LGR8 antibody. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. Lane 1: human SHG-44 whole cell lysate. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-GPCR LGR8 antigen affinity purified polyclonal antibody at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1% Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for GPCR LGR8 at approximately 86KD. The expected band size for GPCR LGR8 is at 86KD.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC-Fr, WB
Unconjugated
10 µg/$318; 100 µg/$470
RXFP2 / LGR8 Antibody - Anti-RXFP2 / LGR8 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
RXFP2 / LGR8 Antibody - Immunohistochemistry image at a dilution of 1:290 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$440; 200 µl/$468
RXFP2 / LGR8 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RXFP2 / LGR8 Antibody - Western blot testing of human SHG-44 cell lysate with RXFP2 antibody at 0.5ug/ml. Predicted molecualr weight ~86 kDa.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal Antibody
Human
Flo, WB
Unconjugated
100 µg/$575
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa692-721) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa692-721) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa692-721) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa692-721) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa692-721) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa692-721) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
RXFP2 / LGR8 Antibody - Western blot analysis of extracts from Jurkat cells, using RXFP2 antibody.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
RXFP2 / LGR8 Antibody - Western blot analysis of the lysates from HUVECcells using RXFP2 antibody.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa103-152) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
RXFP2 / LGR8 Antibody - Western blot analysis of lysates from Jurkat cells, using RXFP2 Antibody. The lane on the right is blocked with the synthesized peptide.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa113-162) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa737-754) Antibody
Human
ELISA
Unconjugated
200 µg/$1,109
RXFP2 / LGR8 Antibody - RXFP2 Antibody western blot of Ramos cell line lysates (35 ug/lane). The RXFP2 antibody detected the RXFP2 protein (arrow).
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa692-721) Antibody
Human
WB
Unconjugated
400 µl/$393
RXFP2 / LGR8 Antibody - RXFP2 / LGR8 antibody Western Blot of Jurkat.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal (aa653-702) Antibody
Human
WB
Unconjugated
100 µl/$424
RXFP2 / LGR8 Antibody - Western blot analysis of extracts of various cell lines, using RXFP2 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
RXFP2 / LGR8 Antibody - Western blot analysis of extracts of various cell lines, using RXFP2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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RXFP2 / LGR8 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 35 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).