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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
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Unfortunately, the antibody (ID:192366) is no longer available.
Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page.
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IL-1B / IL-1 Beta
interleukin 1, beta
IL-1 Beta is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Colorectal cancer chemoprevention by 2 beta-cyclodextrin inclusion compounds of auraptene and 4’-geranyloxyferulic acid. Takuji Tanaka, Mariangela B.M. de Azevedo, Nelson Dura´n, Joel B. Alderete, Francesco Epifano, Salvatore Genovese, Mayu Tanaka, Takahiro Tanaka, Massimo Curini. International journal of cancer. Journal international du cancer. 2010 126:830-40. (IHC-P; Mouse)[Full Text Article]
Trimeric form of intracellular ATP synthase subunit of Aggregatibacter actinomycetemcomitans binds human interleukin-1. Paino A, Tuominen H, Jskelinen M, Alanko J, Nuutila J, Asikainen SE, Pelliniemi LJ, Pllnen MT, Chen C, Ihalin R. PloS one. 2011 6:e18929.
Interleukin-1 is internalised by viable Aggregatibacter actinomycetemcomitans biofilm and locates to the outer edges of nucleoids. Paino A, Lohermaa E, Sormunen R, Tuominen H, Korhonen J, Pllnen MT, Ihalin R. Cytokine. 2012 60:565-74. (IHC, EM; Bacteria)
Serum soluble interleukin 7 receptor is strongly associated with lupus nephritis in patients with systemic lupus erythematosus. Badot V, Luijten RK, van Roon JA, Depresseux G, Aydin S, Van den Eynde BJ, Houssiau FA, Lauwerys BR. Annals of the rheumatic diseases. 2013 72:453-6. (IHC-Fr; Human)
Related Antibodies: LS-C18827.
Maternal immune activation evoked by polyinosinic:polycytidylic acid does not evoke microglial cell activation in the embryo. Smolders S, Smolders SM, Swinnen N, Gärtner A, Rigo JM, Legendre P, Brône B. Frontiers in cellular neuroscience. 2015 9:301. (Flo; Mouse)[Full Text Article]
Related Antibodies: LS-C184791.
p65-Dependent production of interleukin-1 beta by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts. Schulze J, Weber K, Baranowsky A, Streichert T, Lange T, Spiro AS, Albers J, Seitz S, Zustin J, Amling M, Fehse B, Schinke T. Cancer letters. 2012 Apr;317:106-13. [Full Text Article]
Related Antibodies: LS-C18827.
Ontogeny and the effects of in utero brain ischemia on interleukin-1 beta and interleukin-6 protein expression in ovine cerebral cortex and white matter. Sadowska GB, Threlkeld SW, Flangini A, Sharma S, Stonestreet BS. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2012 Oct;30:457-63. [Full Text Article]
Related Antibodies: LS-C42757.