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ICAM-1 / CD54

intercellular adhesion molecule 1

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

Gene Name: intercellular adhesion molecule 1
Family/Subfamily: ICAM , not assigned-ICAM
Synonyms: ICAM1, BB2, CD54 antigen, CD54, ICAM-1, p3.58
Target Sequences: NM_000201 NP_000192.2 P05362

Publications (2)

1
Astaxanthin Inhibits Expression of Retinal Oxidative Stress and Inflammatory Mediators in Streptozotocin-Induced Diabetic Rats. Yeh PT, Huang HW, Yang CM, Yang WS, Yang CH. PloS one. 2016 11:e0146438. (IHC; Rat) [Full Text Article] [PubMed:26765843] [PMC:PMC4713224] Related Antibodies: LS-B1850.
2
Immunomodulatory LncRNA on antisense strand of ICAM-1 augments SARS-CoV-2 infection-associated airway mucoinflammatory phenotype. Dinesh Devadoss, Arpan Acharya, Marko Manevski, Dominika Houserova, Michael D Cioffi, Kabita Pandey, Madhavan Nair, Prem Chapagain, Mehdi Mirsaeidi, Glen M Borchert, Siddappa N Byrareddy, Hitendra S Chand. iScience. 2022 August;25:104685. [Full Text Article] [PubMed:35789750] [PMC:PMC9242679]

☰ Filters
Products
Proteins (37)
Over-Expression Lysate (2)
Recombinant (35)
ICAM-1 / CD54 (37)
SDS-PAGE (5)
Preservative Free (1)
No (37)
6His, C-terminus (2)
Fc, C-terminus (2)
GST (3)
His (6)
His, N-Terminal (1)
His,C-terminus (4)
His-Fc (1)
His-GST (1)
His-T7 (2)
Human IgG Fc, C-terminus (1)
Human IgG1 Fc, C-terminus (1)
Human Mutant IgG1 Fc (1)
Mouse Mutant IgG2a Fc (1)
Myc-DDK (Flag) (3)
Dog (1)
Human (23)
Mouse (8)
Pig (1)
Rat (3)
293T Cells (1)
CHO Cells (8)
E. coli (10)
HEK 293 Cells (8)
Human Cells (6)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (9)
Low endotoxin level (21)
Biologically active (4)
Select
CHO Cells
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
49.5 kDa
10 µg/$268; 50 µg/$349
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
76.8kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Select
E. coli
GST
76.9 kD
1 mg/$1,307; 100 µg/$410; 20 µg/$317
ICAM-1 / CD54 Protein
Select
CHO Cells
None
76.1 kDa
25 µg/$698
ICAM-1 / CD54 Protein
Select
CHO Cells
None
76.1 kDa
25 µg/$575
ICAM-1 / CD54 Protein
Select
CHO Cells
None
76.1 kDa
25 µg/$575
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.7 kDa
100 µg/$926
ICAM-1 / CD54 Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human ICAM1 consists of 464 amino acids and has a predicted molecular mass of 51 kDa. As a result of glycosylation, the apparent molecular mass of rhICAM1 is approxiamtely 65-70 kDa in SDS-PAGE under reducing conditions.
50 µg/$480; 1 mg/$2,261
ICAM-1 / CD54 Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human ICAM1 consists of 459 amino acids and has a predicted molecular mass of 51 kDa. As a result of glycosylation, it migrates with an apparent molecular mass of 70-80 kDa in SDS-PAGE under reducing conditions.
100 µg/$480
ICAM-1 / CD54 Protein
Select
HEK 293 Cells
Human IgG Fc, C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human ICAM1 consists of 691 amino acids and predicts a molecular mass of 76.2 kDa.
100 µg/$348; 1 mg/$1,691
ICAM-1 / CD54 Protein - Recombinant Intercellular Adhesion Molecule 1 By SDS-PAGE
Select
E. coli
His-GST
85.9 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
ICAM-1 / CD54 Protein - Recombinant  Intercellular Adhesion Molecule 1 By SDS-PAGE
Select
E. coli
His-T7
24.1 kDa
10 µg/$290; 50 µg/$500; 100 µg/$797; 200 µg/$997; 1 mg/$2,139; 500 µg/$1,662; 5 mg/$3,487; 2 mg/$2,329
ICAM-1 / CD54 Protein - 12.5% SDS-PAGE of human ICAM1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
84.26 kDa
10 µg/$479; 25 µg/$670
Select
None
49.5 kD
50 µg/$484
Select
293T Cells
Myc-DDK (Flag)
57.83 kDa
20 µg/$150
ICAM-1 / CD54 Protein
Select
HEK 293 Cells
Human IgG1 Fc, C-terminus
SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse ICAM1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 706 amino acids and has a predicted molecular mass of 78.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm ICAM1/Fc monomer is approximately 120-130 kDa due to glycosylation.
100 µg/$480
ICAM-1 / CD54 Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse ICAM1 consists of 469 amino acids after removal of the signal peptide. and has a predicted molecular mass of 51.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm ICAM1 is approximately 80-90 kDa due to glycosylation.
50 µg/$379; 500 µg/$1,538
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
51.7 kDa
50 µg/$721
Select
Human Cells
His-Fc
Less than 1.0 EU/µg protein (determined by LAL method).
78.3 kDa
100 µg/$926
ICAM-1 / CD54 Protein - Purified recombinant protein ICAM1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
55.2 kDa
20 µg/$1,107
ICAM-1 / CD54 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
57.83 kDa
100 µg/$494
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
51 kDa
50 µg/$843
Select
CHO Cells
Human Mutant IgG1 Fc
Less than 0.06 EU/µg protein (determined by LAL method).
100 µg/$470
Select
CHO Cells
Mouse Mutant IgG2a Fc
Less than 0.06 EU/µg protein (determined by LAL method).
50 µg/$358
Select
E. coli
452 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
49.83 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Viewing 1-25 of 37 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).