Target
ICAM-1 / CD54
Synonyms
ICAM1 | BB2 | CD54 antigen | CD54 | ICAM-1 | p3.58
Conjugations
Unconjugated
Tag
Mouse Mutant IgG2a Fc
Expression System
CHO Cells
Source Species
Hamster-Chinese
Purification
Greater than 98% by SDS-PAGE
Bio-Activity
Shows the biological function of the CD54 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Non-lytic: Acts as a long lasting fusion protein which only binds to the receptor. Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC)..
Endotoxin
Less than 0.06 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from PBS
Storage
Store lyophilized at -20°C for up to 1 year. Once reconstituted store at 4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee