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CD53

CD53 molecule

CD53 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein.

Gene Name: CD53 molecule
Family/Subfamily: Tetraspan , not assigned-Tetraspan
Synonyms: CD53, CD53 antigen, CD53 molecule, CD53 tetraspan antigen, Cell surface antigen, Leukocyte surface antigen CD53, Transmembrane glycoprotein, Tetraspanin-25, Tspan-25, CD53 glycoprotein, Cell surface glycoprotein CD53, MOX44, TSPAN25
Target Sequences: NM_000560 NP_000551.1 P19397

Publications (1)

1
The tetraspanin web revisited by super-resolution microscopy. Zuidscherwoude M, Göttfert F, Dunlock VM, Figdor CG, van den Bogaart G, van Spriel AB. Scientific reports. 2015 5:12201. (ICC; Human) [Full Text Article] [PubMed:26183063] [PMC:PMC4505338]

☰ Filters
Antibodies (43)
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Over-Expression Lysate (2)
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CD53 (48)
Human (36)
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Cynomolgus (2)
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mouse (31)
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monoclonal mc (31)
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CD53 Rabbit anti-Cynomolgus Polyclonal Antibody
Cynomolgus
ELISA, IP, WB
Unconjugated
100 µl/$412
CD53 Antibody - Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CD53 mouse mAb with DAB staining.
Select
CD53 Mouse anti-Human Monoclonal (7A8D3) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$459
Select
CD53 Mouse anti-Human Monoclonal (MEM-53) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
0.2 mg/$471
Select
CD53 Rabbit anti-Mouse Polyclonal Antibody
Mouse
IP, WB
Unconjugated
100 µl/$412
CD53 Antibody - Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CD53 mouse mAb with DAB staining.
Select
CD53 Mouse anti-Human Monoclonal (1H2C7) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$459
Select
CD53 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo
Biotin Conjugated
100 µg/$626
Select
CD53 Mouse anti-Human Monoclonal (Concentrated) (MEM-53) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Concentrated
0.1 mg/$453
Select
CD53 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
200 µg/$732
Select
CD53 Mouse anti-Human Monoclonal (HRP) Antibody
Human
Flo, IHC, IP, WB
HRP Conjugated
100 µl/$951
Select
CD53 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC, IP, WB
Biotin Conjugated
100 µl/$951
Select
CD53 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IP, WB
FITC Conjugated
100 µl/$951
Select
CD53 Mouse anti-Human Monoclonal (PE) Antibody
Human
Flo, IHC, IP, WB
PE Conjugated
100 µl/$951
CD53 Antibody - Human peripheral blood lymphocytes stained with purified MEM-53, followed by anti-mouse IgG FITC
Select
CD53 Mouse anti-Human Monoclonal (MEM-53) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$272
Select
CD53 Mouse anti-Human Monoclonal (MEM-53) Antibody
Human
Flo, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$302
Select
CD53 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IP
Unconjugated
100 µg/$558
CD53 Antibody - Human peripheral blood lymphocytes stained with purified HI29, followed by anti-mouse IgG FITC
Select
CD53 Mouse anti-Human Monoclonal (HI29) Antibody
Human
Flo, IHC, IHC-Fr
Unconjugated
100 µg/$272
Select
CD53 Mouse anti-Human Monoclonal (FITC) (MEM-53) Antibody
Human
Flo, Func, IHC-Fr, IP, WB
FITC Conjugated
100 Tests/$337
CD53 Antibody - Surface staining of CD53 in human peripheral blood cells with anti-CD53 (MEM-53) PE.
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CD53 Mouse anti-Human Monoclonal (PE) (MEM-53) Antibody
Human
Flo, Func, IHC-Fr, IP, WB
PE Conjugated
100 Tests/$365
CD53 Antibody - SDS-PAGE Analysis of Purified, BSA-Free CD53 Antibody (clone 63-5A3). Confirmation of Integrity and Purity of the Antibody.
Select
CD53 Mouse anti-Human Monoclonal (63-5A3) Antibody
Human
Flo, IF
Unconjugated
20 µg/$371; 100 µg/$574
CD53 Antibody - SDS-PAGE Analysis of Purified, BSA-Free CD53 Antibody (clone 63-5A3). Confirmation of Integrity and Purity of the Antibody.
Select
CD53 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (63-5A3) Antibody
Human
Flo, IF
Unconjugated, Azide-free, BSA-free
100 µg/$574
CD53 Antibody - SDS-PAGE Analysis of Purified, BSA-Free CD53 Antibody (clone 161-2). Confirmation of Integrity and Purity of the Antibody.
Select
CD53 Mouse anti-Human Monoclonal (161-2) Antibody
Human
Flo, IF
Unconjugated
20 µg/$371; 100 µg/$574
CD53 Antibody - SDS-PAGE Analysis of Purified, BSA-Free CD53 Antibody (clone 161-2). Confirmation of Integrity and Purity of the Antibody.
Select
CD53 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (161-2) Antibody
Human
Flo, IF
Unconjugated, Azide-free, BSA-free
100 µg/$574
CD53 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer at dilution 1:100
Select
CD53 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
CD53 Mouse anti-Human Monoclonal (B400) Antibody
Human
Flo, IP
Unconjugated
0.2 mg/$328
CD53 Antibody - Anti-CD53 rabbit polyclonal antibody at 1:500 dilution. Lane A: Mouse Brain tissue lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 24 kDa. Observed band size: 24 kDa.
Select
CD53 Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
ELISA, WB
Unconjugated, Preservative Free
100 µl/$412
Viewing 1-25 of 48 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).