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Unfortunately, the antibody (ID:131558) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



c-Kit / CD117

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. KIT signaling is modulated by protein phosphatases, and by rapid internalization and degradation of the receptor. Activated KIT promotes phosphorylation of the protein phosphatases PTPN6/SHP-1 and PTPRU, and of the transcription factors STAT1, STAT3, STAT5A and STAT5B. Promotes phosphorylation of PIK3R1, CBL, CRK (isoform Crk-II), LYN, MAPK1/ERK2 and/or MAPK3/ERK1, PLCG1, SRC and SHC1.

Gene Name: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Family/Subfamily: Protein Kinase , PDGF Receptor
Synonyms: KIT, C-Kit, CD117, PBT, Piebald trait, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Soluble KIT variant 1, Tyrosine-protein kinase Kit, p145 c-kit, CD117 antigen
Target Sequences: NM_000222 NP_000213.1 P10721

Filtered By: None
Target
c-kit-cd117 (563)
Reactivity
Human (455)
Mouse (143)
Rat (18)
Bat (1)
Bovine (12)
Chicken (6)
Cynomolgus monkey (2)
Dog (7)
Goat (4)
Horse (4)
Monkey (12)
Pig (6)
Primate (12)
Rabbit (3)
Application
IHC (59)
IHC-Fr (11)
IHC-P (37)
WB (242)
Flo (131)
DB (160)
ELISA (293)
Func (4)
ICC (5)
IF (42)
IP (29)
Neut (7)
Host
rabbit (402)
mouse (102)
goat (3)
rat (56)
Isotype
IgG (339)
IgG1 (47)
IgG1,k (12)
IgG2a (30)
IgG2a,k (1)
IgG2b (40)
IgG2b,k (18)
IgM (2)
Clonality
monoclonal mc (161)
polyclonal pc (402)
Clone
104D2 (7)
12A8 (1)
15B (1)
1C5 (1)
1E2 (1)
1F6 (1)
2B5 (1)
2B8 (29)
2B8/BM (1)
2C1 (2)
2c75 (4)
2E3 (1)
3C1 (4)
3F9 (1)
4F7 (1)
57A5 (6)
5F6 (1)
6G12 (1)
8D7 (1)
8D7B4, 8D7D4, 7H6B2, 7H6B12 (2)
9A11 (1)
A3C6E2 (2)
ACK2 (5)
ACK4 (4)
C117/370 (2)
C117/370 + KIT/982 + KIT/983 (2)
CLDA117 (2)
K45 (2)
KIT/982 (2)
KIT/983 (2)
NU-c-kit (3)
SP26 (1)
T595 (1)
X1 (1)
YB5.B8 (4)
YR145 (1)
Format
AP Conjugated (48)
APC (3)
APC Conjugated (53)
Azide-free (45)
Biotin Conjugated (60)
Cy5 Conjugated (5)
Cy5.5 Conjugated (1)
Cy7 Conjugated (5)
FITC Conjugated (62)
HRP Conjugated (50)
Low Endotoxin (1)
PE (5)
PE Conjugated (63)
Ready-to-Use (1)
RPE Conjugated (3)
SPRD Conjugated (2)
Unconjugated (211)
Epitope
pTyr936 (16)
N-Terminus (10)
pTyr719 (10)
pTyr730 (9)
aa807-836 (8)
pSer716 (8)
pSer739 (8)
pSer746 (8)
pSer821 (8)
pSer891 (8)
pSer959 (8)
pThr274 (8)
pThr354 (8)
pThr357 (8)
pThr718 (8)
pTyr362 (8)
pTyr547 (8)
pTyr553 (8)
pTyr570 (8)
pTyr578 (8)
pTyr823 (8)
pTyr900 (8)
aa259-288 (7)
aa334-361 (7)
aa347-376 (7)
aa532-562 (7)
aa547-577 (7)
aa563-592 (7)
aa691-720 (7)
aa715-744 (7)
aa731-761 (7)
aa878-905 (7)
aa921-951 (7)
aa944-974 (7)
pTyr721 (7)
C-Terminus (6)
Internal (6)
aa100-300 (6)
aa680-711 (6)
aa546-976 (4)
pTyr703 (4)
aa321-520 (3)
aa343-527 (3)
Cytoplasmic Domain (2)
Extracellular Domain (2)
aa912-941 (2)
Glu930 (1)
Ser715 (1)
Tyr703 (1)
Tyr730 (1)
aa1-976 (1)
aa25-519 (1)
aa252-281 (1)
aa26-285 (1)
aa26-520 (1)
aa336-367 (1)
aa339-369 (1)
aa340-369 (1)
aa527-553 (1)
aa553-582 (1)
aa556-585 (1)
aa660-740 (1)
aa685-697 (1)
aa688-718 (1)
aa688-737 (1)
aa699-728 (1)
aa708-737 (1)
aa719-723 (1)
aa724-753 (1)
aa880-960 (1)
aa881-930 (1)
aa885-915 (1)
aa9-40 (1)
aa906-955 (1)
aa914-941 (1)
aa925-976 (1)
aa934-938 (1)
aa937-966 (1)
Publications
No (562)
Yes (1)
Showing 1-25 out of 563 results
Anti-c-Kit / CD117 Antibody (Extracellular Domain) IHC-plus™ LS-A9389

Rabbit Polyclonal to Human c-Kit / CD117
Human
IHC-P
Unconjugated
Anti-c-Kit / CD117 Antibody (clone X1) IHC-plus™ LS-B6060

Mouse Monoclonal [clone X1] (IgG2b,k) to Human c-Kit / CD117
Human
ELISA IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody LS-C78828

Rabbit Polyclonal (IgG) to Human c-Kit / CD117
Rat, Human
Flo IF IHC
Unconjugated
Anti-c-Kit / CD117 Antibody (clone ACK2) LS-C107133

Rat Monoclonal [clone ACK2] (IgG2b,k) to Mouse c-Kit / CD117
Mouse
Flo IHC-Fr IP
Unconjugated
Anti-c-Kit / CD117 Antibody (Internal, clone 15B) LS-C191740

Rabbit Polyclonal [clone 15B] (IgG) to Human c-Kit / CD117
Mouse, Human
ELISA IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone NU-c-kit, FITC) LS-C140410

Mouse Monoclonal [clone NU-c-kit] (IgG) to Human c-Kit / CD117
Human
Flo
FITC Conjugated
Anti-c-Kit / CD117 Antibody (Cytoplasmic Domain) IHC-plus™ LS-B5194

Rabbit Polyclonal (IgG) to Human c-Kit / CD117
Dog, Human
IHC-P
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 4F7) IHC-plus™ LS-B6059

Mouse Monoclonal [clone 4F7] (IgG) to Human c-Kit / CD117
Human
ELISA IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 6G12) IHC-plus™ LS-B6057

Mouse Monoclonal [clone 6G12] (IgG2b,k) to Human c-Kit / CD117
Human
ELISA IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (aa26-520) LS-C150051

Goat Polyclonal (IgG) to Human c-Kit / CD117
Human
Flo IHC-P Neut WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone ACK4) LS-C34582

Rat Monoclonal [clone ACK4] (IgG2a) to Mouse c-Kit / CD117
Mouse
Flo IHC-Fr
Unconjugated
Anti-c-Kit / CD117 Antibody (aa25-519) LS-C150245

Goat Polyclonal (IgG) to Mouse c-Kit / CD117
Mouse
Flo IHC WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 104D2) LS-C40873

Mouse Monoclonal [clone 104D2] (IgG1) to Human c-Kit / CD117
Bovine, Human, Monkey
Flo IF IP
Unconjugated
Anti-c-Kit / CD117 Antibody (clone K45) LS-C88025

Mouse Monoclonal [clone K45] (IgG2a) to Human c-Kit / CD117
Human
IF IHC-Fr
Unconjugated
Anti-c-Kit / CD117 Antibody (phospho-Ser959, PE) LS-C261310

Rabbit Polyclonal (IgG) to Human c-Kit / CD117
Human
DB ELISA
PE Conjugated
Anti-c-Kit / CD117 Antibody (clone ACK2, PE, Cy7) LS-C107226

Rat Monoclonal [clone ACK2] (IgG2b,k) to Mouse c-Kit / CD117
Mouse
Flo
PE, Cy7 Conjugated
Anti-c-Kit / CD117 Antibody (FITC) LS-C14157

Mouse Monoclonal (IgG1) to Human c-Kit / CD117
Human
Flo
FITC Conjugated
Anti-c-Kit / CD117 Antibody (clone 5F6) IHC-plus™ LS-B6058

Mouse Monoclonal [clone 5F6] (IgG2b,k) to Human c-Kit / CD117
Human
ELISA IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (aa912-941, PE) LS-C282542

Rabbit Polyclonal (IgG) to Human c-Kit / CD117
Mouse, Human
ELISA Flo IF IHC WB
PE Conjugated
Anti-c-Kit / CD117 Antibody (clone 2B8/BM) LS-C187513

Mouse Monoclonal [clone 2B8/BM] (IgG1) to Pig c-Kit / CD117
Pig
Flo IHC-Fr IP WB
Unconjugated
Anti-c-Kit / CD117 Antibody (aa9-40) LS-C97561

Rabbit Polyclonal to Human c-Kit / CD117
Human, Primate
Flo IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 9A11) IHC-plus™ LS-B10212

Mouse Monoclonal [clone 9A11] (IgG2a) to Human c-Kit / CD117
Human
IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (Ser715) LS-C177669

Rabbit Polyclonal to Human c-Kit / CD117
Mouse, Rat, Human
IF WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone 2C1) LS-C175534

Mouse Monoclonal [clone 2C1] (IgG1) to Human c-Kit / CD117
Human
IHC-P WB
Unconjugated
Anti-c-Kit / CD117 Antibody (clone A3C6E2) LS-C179621

Mouse Monoclonal [clone A3C6E2] (IgG1) to Human c-Kit / CD117
Human
Flo IP
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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