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PathPlusTM UCHL1 / PGP9.5 Antibodies
UCHL1 is a deubiquitinating enzyme found in neurons and neuroendocrine cells. UCHL1 functions to promote neuronal differentiation and regulates autophagy. UCHL1 is also considered an oncogene; mice engineered to overexpress UCHL1 demonstrate a propensity for lymphogenesis and malignancy, and abnormal expression of UCHL1 is seen in some lung and endometrial cancers. It has also been implicated in a number of neurodegenerative disorders including Parkinson’s and Alzheimer’s disease. In immunohistochemistry of normal tissue, UCHL1 is positive in neurons in the central nervous system. It is also present in a number of other tissues and cell types including distal renal tubules, islets of Langerhans, spermatogonia in testis, Leydig cells, oocytes and melanocytes. References: Chemistry & Biology. 10 (9): 837–46. doi:10.1016/j.chembiol.2003.08.010. PMID: 14522054; Leukemia. 2010 Sep;24(9):1641-55, PMID: 20574456; J Exp Clin Cancer Res. 2018 Oct 25;37(1):258, PMID: 30359286; Int J Gynecol Cancer. 2018 May;28(4):675-683, PMID: 29489474

7 PathPlusTM Antibodies
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Antibodies (7)
Primary (7)
UCHL1 / PGP9.5 (7)
Human (4)
Mouse (2)
Rat (2)
Bat (1)
Bovine (1)
Hamster (1)
Horse (1)
Monkey (1)
Pig (1)
Rabbit (1)
Zebrafish (1)
IHC (3)
IHC-P (7)
WB (4)
ELISA (2)
Peptide-ELISA (2)
rabbit (4)
mouse (2)
goat (1)
Product Group
PathPlus Cancer (4)
PathPlus Cancer Pathology (7)
IgG (2)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (5)
1B8-4D2 (1)
Unconjugated (7)
aa150-C-term (1)
aa171-220 (1)
No (7)
UCHL1 / PGP9.5 Antibody - Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Cancer Pathology
Cancer
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa171-220) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
UCHL1 / PGP9.5 Antibody - Anti-UCHL1 / PGP9.5 antibody IHC of human small intestine, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Cancer Pathology
Cancer
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal (1B8-4D2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$485
UCHL1 / PGP9.5 Antibody - Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
UCHL1 / PGP9.5 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
UCHL1 / PGP9.5 Antibody - Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Cancer
UCHL1 / PGP9.5 Goat anti-Human Polyclonal (aa150-C-term) Antibody
Zebrafish, Pig, Horse, Bat, Rabbit, Mouse, Bovine, Rat, Hamster, Human, Monkey
ELISA, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µg/$485
UCHL1 / PGP9.5 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Fast Shipping
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
UCHL1 / PGP9.5 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Fast Shipping
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
UCHL1 / PGP9.5 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer Pathology
Fast Shipping
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
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