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Catalog Number Size Price
LS-A12016-50 50 µg (1 mg/ml) $460 
UCHL1 / PGP9.5 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
UCHL1 / PGP9.5 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
UCHL1 / PGP9.5 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
UCHL1 / PGP9.5 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
UCHL1 / PGP9.5 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
UCHL1 / PGP9.5 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
UCHL1 / PGP9.5 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
UCHL1 / PGP9.5 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PathPlus™ Polyclonal Rabbit anti‑Human UCHL1 / PGP9.5 Antibody (IHC) LS‑A12016

PathPlus™ Polyclonal Rabbit anti‑Human UCHL1 / PGP9.5 Antibody (IHC) LS‑A12016

Antibody:
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-A12016-50

Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal Antibody
Application:
IHC-P
Format:
Unconjugated, Unmodified

Specifications

Description
UCHL1 is a deubiquitinating enzyme found in neurons and neuroendocrine cells. UCHL1 functions to promote neuronal differentiation and regulates autophagy. UCHL1 is also considered an oncogene; mice engineered to overexpress UCHL1 demonstrate a propensity for lymphogenesis and malignancy, and abnormal expression of UCHL1 is seen in some lung and endometrial cancers. It has also been implicated in a number of neurodegenerative disorders including Parkinson’s and Alzheimer’s disease. In immunohistochemistry of normal tissue, UCHL1 is positive in neurons in the central nervous system. It is also present in a number of other tissues and cell types including distal renal tubules, islets of Langerhans, spermatogonia in testis, Leydig cells, oocytes and melanocytes. References: Chemistry & Biology. 10 (9): 837–46. doi:10.1016/j.chembiol.2003.08.010. PMID: 14522054; Leukemia. 2010 Sep;24(9):1641-55, PMID: 20574456; J Exp Clin Cancer Res. 2018 Oct 25;37(1):258, PMID: 30359286; Int J Gynecol Cancer. 2018 May;28(4):675-683, PMID: 29489474
Target
Human UCHL1 / PGP9.5
Synonyms
UCHL1 | Ubiquitin C-terminal hydrolase | PARK5 | PGP9.5 | PGP95 | Ubiquitin thioesterase L1 | Neuron cytoplasmic protein 9.5 | PGP 9.5 | Uch-L1 | Ubiquitin carboxyl-terminal esterase L1 | HEL-117 | NDGOA | HEL-S-53 | SPG79
Host
Rabbit
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
LP-12016, synthetic peptide
Applications
  • IHC - Paraffin (5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About UCHL1 / PGP9.5
P09936 NM_004181 NP_004172.2

Validation

UCHL1 / PGP9.5 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

UCHL1 / PGP9.5 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

UCHL1 / PGP9.5 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

UCHL1 / PGP9.5 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ UCHL1 / PGP9.5 Antibody for IHC LS-A12016 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/5/2024