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Catalog Number Size Price
LS-B5981-50 50 µl (1 mg/ml) $440 
UCHL1 / PGP9.5 Antibody - Anti-UCHL1 / PGP9.5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
UCHL1 / PGP9.5 Antibody - Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
UCHL1 / PGP9.5 Antibody - Western blot analysis of lysates from 293 cells, using PGP9.5 Antibody. The lane on the right is blocked with the synthesized peptide.
UCHL1 / PGP9.5 Antibody - Anti-UCHL1 / PGP9.5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
UCHL1 / PGP9.5 Antibody - Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
UCHL1 / PGP9.5 Antibody - Western blot analysis of lysates from 293 cells, using PGP9.5 Antibody. The lane on the right is blocked with the synthesized peptide.
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PathPlus™ Polyclonal Rabbit anti‑Human UCHL1 / PGP9.5 Antibody (aa171‑220, IHC, WB) LS‑B5981

PathPlus™ Polyclonal Rabbit anti‑Human UCHL1 / PGP9.5 Antibody (aa171‑220, IHC, WB) LS‑B5981

Note: This antibody replaces LS-C118557
Antibody:
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa171-220) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B5981-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
UCHL1 / PGP9.5 Rabbit anti-Human Polyclonal (aa171-220) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
UCHL1 is a deubiquitinating enzyme found in neurons and neuroendocrine cells. UCHL1 functions to promote neuronal differentiation and regulates autophagy. UCHL1 is also considered an oncogene; mice engineered to overexpress UCHL1 demonstrate a propensity for lymphogenesis and malignancy, and abnormal expression of UCHL1 is seen in some lung and endometrial cancers. It has also been implicated in a number of neurodegenerative disorders including Parkinson’s and Alzheimer’s disease. In immunohistochemistry of normal tissue, UCHL1 is positive in neurons in the central nervous system. It is also present in a number of other tissues and cell types including distal renal tubules, islets of Langerhans, spermatogonia in testis, Leydig cells, oocytes and melanocytes. References: Chemistry & Biology. 10 (9): 837–46. doi:10.1016/j.chembiol.2003.08.010. PMID: 14522054; Leukemia. 2010 Sep;24(9):1641-55, PMID: 20574456; J Exp Clin Cancer Res. 2018 Oct 25;37(1):258, PMID: 30359286; Int J Gynecol Cancer. 2018 May;28(4):675-683, PMID: 29489474
Target
Human UCHL1 / PGP9.5
Synonyms
UCHL1 | Ubiquitin C-terminal hydrolase | PARK5 | PGP9.5 | PGP95 | Ubiquitin thioesterase L1 | Neuron cytoplasmic protein 9.5 | PGP 9.5 | Uch-L1 | Ubiquitin carboxyl-terminal esterase L1 | HEL-117 | NDGOA | HEL-S-53 | SPG79
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human PGP9.5. (AA Range: 171-220)
Epitope
aa171-220
Specificity
PGP9.5 Antibody detects endogenous levels of total PGP9.5 protein.
Applications
  • IHC
  • IHC - Paraffin (1:200)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blot: Predicted MW 24 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About UCHL1 / PGP9.5
P09936 NM_004181 NP_004172.2

Validation

UCHL1 / PGP9.5 Antibody - Anti-UCHL1 / PGP9.5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-UCHL1 / PGP9.5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-UCHL1 / PGP9.5 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

UCHL1 / PGP9.5 Antibody - Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-UCHL1 / PGP9.5 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.

LSBio Ratings

PathPlus™ UCHL1 / PGP9.5 Antibody (aa171-220) for IHC, WB/Western LS-B5981 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/24/2021