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PathPlusTM ACE / CD143 Antibodies
ACE (Angiotensin-converting enzyme, CD143) is an enzyme involved in catalyzing the conversion of angiotensin I into the physiologically active angiotensin II. It has a central role in the renin-angiotensin system, which is involved in regulating blood pressure and fluid volume in the body. The 287 bp Alu repeat element in this gene is correlated with levels of circulating ACE enzyme and with cardiovascular patho-physiologies. Variants in ACE are also associated with Alzheimer’s disease, where deregulated levels of the protein have been found. In immunohistochemistry, ACE has positive staining in the lung capillary endothelium, basal ganglia neuropil, granulosa cells, Leydig cells, proximal renal tubule brush borders, the uterus, male genitalia, and endothelial cells of small or medium arteries. References: Am J Transl Res. 2011 Jan 1; 3(1): 73–80, PMID: 21139807; Alzheimers Res Ther. 2014; 6(3): 27, PMID: 24987467

2 PathPlusTM Antibodies
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Antibodies (2)
Primary (2)
ACE / CD143 (2)
Human (2)
Mouse (2)
Rat (1)
Bovine (1)
Cat (1)
Dog (1)
Guinea pig (1)
Monkey (1)
Rabbit (1)
IHC (2)
IHC-P (2)
WB (2)
mouse (2)
Product Group
PathPlus Neuro (2)
IgG1 (1)
IgG2a (1)
monoclonal mc (2)
Unconjugated (2)
aa1274-1306 (1)
No (2)
ACE / CD143 Antibody - Anti-ACE antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Neuroscience
ACE / CD143 Mouse anti-Human Monoclonal Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Cat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$485
ACE / CD143 Antibody - Anti-ACE / CD143 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
Neuroscience
ACE / CD143 Mouse anti-Human Monoclonal (aa1274-1306) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
0.05 ml/$440
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