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Catalog Number Size Price
LS-B13300-50 50 µl (1 mg/ml) $440 
PDCD1 / CD279 / PD-1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
PDCD1 / CD279 / PD-1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDCD1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDCD1.
PDCD1 / CD279 / PD-1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
PDCD1 / CD279 / PD-1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDCD1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDCD1.
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PathPlus™ Monoclonal Mouse anti‑Human PDCD1 / CD279 / PD‑1 Antibody (clone 11B2, IHC, IF, WB) LS‑B13300

PathPlus™ Monoclonal Mouse anti‑Human PDCD1 / CD279 / PD‑1 Antibody (clone 11B2, IHC, IF, WB) LS‑B13300

Note: This antibody replaces LS-C340095
Antibody:
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (11B2) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B13300-50
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
PDCD1 / CD279 / PD-1 Mouse anti-Human Monoclonal (11B2) Antibody
Application:
IHC, IHC-P, IF, WB, Flo
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
PD1 (Programmed Death Receptor 1, PDCD1, CD279) is an immune checkpoint protein active in T cells that is a target alongside its ligand PDL1 and also CTLA-4 for immunotherapy in lung and other cancers. PD1 is involved in negatively regulating T cell inflammatory activity and, when bound to receptors on tumor cells, can work to subdue tumor suppression by inhibiting the immune response. Targeted inhibition of PD1 itself can therefore function as an anti-cancer therapy by reactivating this response. PD1 is expected to have membranous staining in germinal center associated helper T cells, CD8+ T cells, and Pro-B cells. It is for the identification of subsets of T and B cell lymphomas and nodular lymphocyte predominant Hodgkin lymphomas. References: Alsaab, 2017; Jin, 2011; Francisco, 2010; Fife, 2011; Human Pathol 2008 39(7):1050
Target
Human PDCD1 / CD279 / PD-1
Synonyms
PDCD1 | CD279 | HPD-1 | HPD-l | PD1 | Protein PD-1 | SLEB2 | PD-1 | CD279 antigen | Programmed cell death 1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Clone
11B2
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Full length human recombinant protein of human PDCD1 (NP_005009) produced in HEK293T cell.
Specificity
Human PDCD1 / CD279 / PD-1
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Immunofluorescence (1:100 - 1:900)
  • Western blot (1:2000)
  • Flow Cytometry (1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol, 1% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PDCD1 / CD279 / PD-1
Q15116 NM_005018 NP_005009.2

Validation

PDCD1 / CD279 / PD-1 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ PDCD1 / CD279 / PD-1 Antibody (clone 11B2) for IHC, IF/Immunofluorescence, WB/Western, Flow LS-B13300 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/27/2021