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Catalog Number Size Price
LS-B3910-50 50 µg (0.5 mg/ml) $460 
MYC / c-Myc Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
MYC / c-Myc Antibody - Jurkat extract probed with anti-c-myc monoclonal antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and chemiluminescence. Intact (non-degraded) c-myc with a molecular weight of approximately 62 kD was detected.
MYC / c-Myc Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
MYC / c-Myc Antibody - Jurkat extract probed with anti-c-myc monoclonal antibody. Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and chemiluminescence. Intact (non-degraded) c-myc with a molecular weight of approximately 62 kD was detected.
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PathPlus™ Monoclonal Mouse anti‑Human MYC / c‑Myc Antibody (clone 9E10, aa408‑439, IHC, IF, WB) LS‑B3910

PathPlus™ Monoclonal Mouse anti‑Human MYC / c‑Myc Antibody (clone 9E10, aa408‑439, IHC, IF, WB) LS‑B3910

Note: This antibody replaces LS-C40866
Antibody:
MYC / c-Myc Mouse anti-Human Monoclonal (aa408-439) (9E10) Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B3910-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
MYC / c-Myc Mouse anti-Human Monoclonal (aa408-439) (9E10) Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
MYC (c-Myc) is a multifunctional nuclear phosphoprotein that plays a central role in cell cycle progression, apoptosis and cellular transformation. It is one of the Yamanaka master transcription factors (MYC, OCT4/POU5F1, SOX2 and KLF4) that are involved in transdifferentiation, induced pluripotency and aging. It regulates the transcription of thousands of specific target genes (roughly 15% of all genes), and it generally upregulates their expression. MYC itself is broadly overexpressed in cervical, colorectal, breast, lung, stomach and other cancers. Mutations, rearrangements and translocations of this gene have also been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt’s lymphoma. In immunohistochemistry of normal tissues, MYC has nuclear positivity in all cells with the exception of stroma and glial cells. References: Proceedings of the National Academy of Sciences of the United States of America. 85 (9): 3052–6, PMID: 2834731; PLoS One. 2008;3(10):e3534, PMID: 18953412; Science. 2017 Aug 18;357(6352). pii: eaan2507, PMID: 28818916; Cell. 2016 Dec 15;167(7):1719-1733.e12, PMID: 27984723
Target
Human MYC / c-Myc
Synonyms
MYC | BHLHe39 | C-Myc | MRTL | Myc proto-oncogene protein | Proto-oncogene c-Myc | Rats1 | Transcription factor p64 | v-myc
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
9E10
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human MYC / c-Myc.
Epitope
aa408-439
Specificity
Amino acids 408-439, C-terminal region of human c-myc. Recognizes EQKLISEEDL (Myc-tag).
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml.
Storage
Store at 4°C. Store undiluted.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MYC / c-Myc
P01106 NM_002467 NP_002458.2

Validation

MYC / c-Myc Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)

MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-MYC / c-Myc antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-MYC / c-Myc antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

LSBio Ratings

PathPlus™ MYC / c-Myc Antibody (aa408-439, clone 9E10) for IHC, IF/Immunofluorescence, WB/Western, IP, Flow, ELISA LS-B3910 has an LSBio Rating of
Publications (4.4)
Laboratory Validation Score (5)

Publications (5)

Epstein-Barr virus latent membrane protein 1 induces cancer stem/progenitor-like cells in nasopharyngeal epithelial cell lines. Kondo S, Wakisaka N, Muramatsu M, Zen Y, Endo K, Murono S, Sugimoto H, Yamaoka S, Pagano JS, Yoshizaki T. Journal of virology. 2011 85:11255-64. (WB; Human)

Human and mouse ZFY genes produce a conserved testis-specific transcript encoding a zinc finger protein with a short acidic domain and modified transactivation potential. Decarpentrie F, Vernet N, Mahadevaiah SK, Longepied G, Streichemberger E, Aknin-Seifer I, Ojarikre OA, Burgoyne PS, Metzler-Guillemain C, Mitchell MJ. Human molecular genetics. 2012 21:2631-45.

Autoregulation of MARCH1 expression by dimerization and autoubiquitination. Bourgeois-Daigneault MC, Thibodeau J. Journal of immunology (Baltimore, Md. : 1950). 2012 188:4959-70.

Staphylococcus aureus adherence to Candida albicans hyphae is mediated by the hyphal adhesin Als3p. Peters BM, Ovchinnikova ES, Krom BP, Schlecht LM, Zhou H, Hoyer LL, Busscher HJ, van der Mei HC, Jabra-Rizk MA, Shirtliff ME. Microbiology (Reading, England). 2012 158:2975-86.

Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair. Robu M, Shah RG, Petitclerc N, Brind'Amour J, Kandan-Kulangara F, Shah GM. Proceedings of the National Academy of Sciences of the United States of America. 2013 110:1658-63.

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Requested From: United States
Date Requested: 5/20/2024