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Catalog Number Size Price
LS-B7576-100 100 µl (1 mg/ml) $460 
MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
MYC / c-Myc Antibody - Western blot analysis of lysates from ovary cancer cells, using MYC Antibody. The lane on the right is blocked with the synthesized peptide.
MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
MYC / c-Myc Antibody - Western blot analysis of lysates from ovary cancer cells, using MYC Antibody. The lane on the right is blocked with the synthesized peptide.
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PathPlus™ Polyclonal Rabbit anti‑Human MYC / c‑Myc Antibody (aa25‑74, IHC, WB) LS‑B7576

PathPlus™ Polyclonal Rabbit anti‑Human MYC / c‑Myc Antibody (aa25‑74, IHC, WB) LS‑B7576

Note: This antibody replaces LS-C118188
Antibody:
MYC / c-Myc Rabbit anti-Human Polyclonal (aa25-74) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B7576-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
MYC / c-Myc Rabbit anti-Human Polyclonal (aa25-74) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
MYC (c-Myc) is a multifunctional nuclear phosphoprotein that plays a central role in cell cycle progression, apoptosis and cellular transformation. It is one of the Yamanaka master transcription factors (MYC, OCT4/POU5F1, SOX2 and KLF4) that are involved in transdifferentiation, induced pluripotency and aging. It regulates the transcription of thousands of specific target genes (roughly 15% of all genes), and it generally upregulates their expression. MYC itself is broadly overexpressed in cervical, colorectal, breast, lung, stomach and other cancers. Mutations, rearrangements and translocations of this gene have also been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt’s lymphoma. In immunohistochemistry of normal tissues, MYC has nuclear positivity in all cells with the exception of stroma and glial cells. References: Proceedings of the National Academy of Sciences of the United States of America. 85 (9): 3052–6, PMID: 2834731; PLoS One. 2008;3(10):e3534, PMID: 18953412; Science. 2017 Aug 18;357(6352). pii: eaan2507, PMID: 28818916; Cell. 2016 Dec 15;167(7):1719-1733.e12, PMID: 27984723
Target
Human MYC / c-Myc
Synonyms
MYC | BHLHe39 | C-Myc | MRTL | Myc proto-oncogene protein | Proto-oncogene c-Myc | Rats1 | Transcription factor p64 | v-myc
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human MYC. (AA Range: 25-74)
Epitope
aa25-74
Specificity
This antibody detects endogenous levels of total MYC protein.
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:20000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blot: Predicted MW 48 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MYC / c-Myc
P01106 NM_002467 NP_002458.2

Validation

MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-MYC / c-Myc antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-MYC / c-Myc antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

LSBio Ratings

PathPlus™ MYC / c-Myc Antibody (aa25-74) for IHC, WB/Western LS-B7576 has an LSBio Rating of
Laboratory Validation Score (5)

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 6/18/2024