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Catalog Number Size Price
LS-B2791-0.05 0.05 mg (1 mg/ml) $460 
MYC / c-Myc Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
MYC / c-Myc Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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PathPlus™ Monoclonal Mouse anti‑Human MYC / c‑Myc Antibody (clone 9E10, aa400‑450, IHC, WB) LS‑B2791

PathPlus™ Monoclonal Mouse anti‑Human MYC / c‑Myc Antibody (clone 9E10, aa400‑450, IHC, WB) LS‑B2791

Note: This antibody replaces LS-C46098
Antibody:
MYC / c-Myc Mouse anti-Human Monoclonal (aa400-450) (9E10) Antibody
Application:
IHC, IHC-P, WB, IP, Flo
Reactivity:
Human, All species
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$460
LS-B2791-0.05
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
MYC / c-Myc Mouse anti-Human Monoclonal (aa400-450) (9E10) Antibody
Application:
IHC, IHC-P, WB, IP, Flo
Reactivity:
Human, All species
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
MYC (c-Myc) is a multifunctional nuclear phosphoprotein that plays a central role in cell cycle progression, apoptosis and cellular transformation. It is one of the Yamanaka master transcription factors (MYC, OCT4/POU5F1, SOX2 and KLF4) that are involved in transdifferentiation, induced pluripotency and aging. It regulates the transcription of thousands of specific target genes (roughly 15% of all genes), and it generally upregulates their expression. MYC itself is broadly overexpressed in cervical, colorectal, breast, lung, stomach and other cancers. Mutations, rearrangements and translocations of this gene have also been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt’s lymphoma. In immunohistochemistry of normal tissues, MYC has nuclear positivity in all cells with the exception of stroma and glial cells. References: Proceedings of the National Academy of Sciences of the United States of America. 85 (9): 3052–6, PMID: 2834731; PLoS One. 2008;3(10):e3534, PMID: 18953412; Science. 2017 Aug 18;357(6352). pii: eaan2507, PMID: 28818916; Cell. 2016 Dec 15;167(7):1719-1733.e12, PMID: 27984723
Target
Human MYC / c-Myc
Synonyms
MYC | BHLHe39 | C-Myc | MRTL | Myc proto-oncogene protein | Proto-oncogene c-Myc | Rats1 | Transcription factor p64 | v-myc
Host
Mouse
Reactivity
Human, All species
Clonality
IgG1 Monoclonal
Clone
9E10
Conjugations
Unconjugated. Also available conjugated with FITC, HRP.
Purification
Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.
Modifications
Unmodified
Immunogen
A synthetic peptide corresponding to the C-Terminus of human MYC
Epitope
aa400-450
Specificity
Used to detect the c-Myc tag.
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Western blot (0.5 - 2 µg/ml)
  • Immunoprecipitation (1 - 5 µg/ml)
  • Flow Cytometry (1 - 5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.4, 15 mM Sodium Azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MYC / c-Myc
P01106 NM_002467 NP_002458.2

Validation

MYC / c-Myc Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)

MYC / c-Myc Antibody - Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-MYC / c-Myc antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

LSBio Ratings

PathPlus™ MYC / c-Myc Antibody (aa400-450, clone 9E10) for IHC, WB/Western, IP, Flow LS-B2791 has an LSBio Rating of
Laboratory Validation Score (5)

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Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/17/2024