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Catalog Number Size Price
LS-B7604-100 100 µl (1 mg/ml) $460 
HDAC6 Antibody - Anti-HDAC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
HDAC6 Antibody - Western blot analysis of lysates from HeLa cells, using HDAC6 Antibody. The lane on the right is blocked with the synthesized peptide.
HDAC6 Antibody - Anti-HDAC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
HDAC6 Antibody - Western blot analysis of lysates from HeLa cells, using HDAC6 Antibody. The lane on the right is blocked with the synthesized peptide.
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PathPlus™ Polyclonal Rabbit anti‑Human HDAC6 Antibody (aa1166‑1215, IHC, WB) LS‑B7604

PathPlus™ Polyclonal Rabbit anti‑Human HDAC6 Antibody (aa1166‑1215, IHC, WB) LS‑B7604

Note: This antibody replaces LS-C118481
Antibody:
HDAC6 Rabbit anti-Human Polyclonal (aa1166-1215) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B7604-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
HDAC6 Rabbit anti-Human Polyclonal (aa1166-1215) Antibody
Application:
IHC, IHC-P, WB, Peptide-ELISA
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
HDAC6 is a histone deacetylase that represses transcription and is involved in cell cycle progression, development, and regulation of gene expression. HDAC6 also plays an important role in cell migration in normal tissue and in cancer via its regulation of tubulin acetylation and depolymerization. Variable levels of HDAC6 dysregulation are associated with survival in different cancer types. For example, HDAC6 overexpression is associated positively with survival in ER-positive breast cancer, cutaneous T-Cell lymphoma and diffuse large B-Cell lymphoma, and with poor prognosis in peripheral T-Cell lymphoma and ER-negative breast cancer. Downregulation of HDAC6 is associated with poor survival in chronic lymphocytic leukemia. In immunohistochemistry of normal tissue, HDAC6 has broad cytoplasmic expression throughout the body, with strongest positivity in seminiferous duct cells and renal tubules. References: J Cancer Res Ther. 2014 Jul-Sep;10(3):469-78, PMID: 25313724; Cold Spring Harb Perspect Med. 2016 Oct; 6(10): a026831, PMID: 27599530; Oncogene. 2007 Aug. 26: 5420–5432, PMID: 17694083; J Cell Sci. 2007 Apr 15;120(Pt 8):1469-79, PMID: 17389687; J Breast Cancer. 2014 Dec; 17(4): 323–331, PMID: 25548579, PMID: 29180246
Target
Human HDAC6
Synonyms
HDAC6 | Histone deacetylase 6 | HD6 | KIAA0901 | JM21
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from human HDAC6. (AA Range: 1166-1215)
Epitope
aa1166-1215
Specificity
HDAC6 Antibody detects endogenous levels of total HDAC6 protein.
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Western Blot: Predicted MW 131 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HDAC6
Q9UBN7 NM_006044 NP_006035.2

Validation

HDAC6 Antibody - Anti-HDAC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-HDAC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-HDAC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

LSBio Ratings

PathPlus™ HDAC6 Antibody (aa1166-1215) for IHC, WB/Western LS-B7604 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/15/2024