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HDAC6

histone deacetylase 6

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Gene Name: histone deacetylase 6
Family/Subfamily: Histone Deacetylase , not assigned-Histone Deacetylase
Synonyms: HDAC6, Histone deacetylase 6, HD6, KIAA0901, JM21
Target Sequences: NM_006044 NP_006035.2 Q9UBN7

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Antibodies (127)
Primary (127)
HDAC6 (127)
Human (107)
Mouse (56)
Rat (24)
Bat (4)
Bovine (3)
Dog (3)
Gibbon (9)
Horse (3)
Monkey (21)
Orangutan (3)
Pig (12)
Rabbit (4)
IHC (52)
IHC-P (26)
WB (112)
Flo (17)
ChrIP (1)
ELISA (29)
ICC (10)
IF (34)
IP (6)
Peptide-ELISA (5)
rabbit (99)
mouse (27)
goat (1)
Product Group
IHCPlus (6)
PathPlus Cancer (2)
IgG (38)
IgG1 (16)
IgG1,k (7)
IgG2b (1)
monoclonal mc (26)
polyclonal pc (101)
3A6 (1)
4G6F9 (1)
ABT-HDAC6 (1)
OTI1B3 (2)
OTI1D10 (2)
OTI1D11 (2)
OTI3E7 (2)
OTI3F9 (2)
OTI3G7 (2)
OTI4C5 (2)
OTI5E6 (2)
APC (4)
APC Conjugated (6)
Biotin Conjugated (10)
Carrier-free (8)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (9)
HRP Conjugated (9)
PE Conjugated (6)
Preservative Free (1)
Unconjugated (76)
aa1038-1204 (8)
aa166-348 (8)
aa560-811 (8)
aa565-813 (8)
N-Terminus (7)
C-Terminus (6)
aa1182-1215 (6)
aa69-118 (4)
pSer22 (4)
1-80 aa (2)
aa1-16 (2)
1140-1220 aa, C-terminal (1)
Ab-22 (1)
His1203 (1)
Internal (1)
Ser22 (1)
aa1100-C-term (1)
aa1128-1215 (1)
aa1165-1215 (1)
aa1166-1215 (1)
aa137-169 (1)
aa160-470 (1)
aa7-56 (1)
No (127)
HDAC6 Antibody - Anti-HDAC6 antibody IHC of human intestine, ganglion cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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HDAC6 Rabbit anti-Human Polyclonal (aa7-56) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
HDAC6 Antibody - Anti-HDAC6 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Cancer
HDAC6 Goat anti-Human Polyclonal (aa1100-C-term) Antibody
Mouse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
HDAC6 Antibody - Immunofluorescence analysis of HeLa cells using HDAC6 antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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HDAC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 100 µl/$389
HDAC6 Antibody - Western blot of HDAC-6 in NIH-3T3 cell lysate with antibody.
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HDAC6 Rabbit anti-Human Polyclonal (aa1-16) Antibody
Mouse, Human
ChrIP, IP, WB
Unconjugated
0.1 mg/$386
HDAC6 Antibody - Anti-HDAC6 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HDAC6 Rabbit anti-Human Polyclonal (aa69-118) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
HDAC6 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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HDAC6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
HDAC6 Antibody - Anti-HDAC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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HDAC6 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
HDAC6 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-HDAC6 mouse monoclonal antibody.
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HDAC6 Mouse anti-Human Monoclonal (OTI1B3) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HDAC6 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-HDAC6 mouse monoclonal antibody.
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HDAC6 Mouse anti-Human Monoclonal (Carrier-free) (OTI1B3) Antibody
Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HDAC6 Antibody - Anti-HDAC6 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HDAC6.
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HDAC6 Mouse anti-Human Monoclonal (OTI4C5) Antibody
Dog, Rat, Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$450
HDAC6 Antibody - Anti-HDAC6 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HDAC6.
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HDAC6 Mouse anti-Human Monoclonal (Carrier-free) (OTI4C5) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
HDAC6 Antibody - Western blot of Phospho-HDAC6 (S22) antibody
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HDAC6 Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
HDAC6 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-HDAC6 mouse monoclonal antibody.
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HDAC6 Mouse anti-Human Monoclonal (OTI5E6) Antibody
Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HDAC6 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-HDAC6 mouse monoclonal antibody.
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HDAC6 Mouse anti-Human Monoclonal (Carrier-free) (OTI5E6) Antibody
Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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HDAC6 Rabbit anti-Human Polyclonal (aa1-16) Antibody
Mouse, Human
IP, WB
Unconjugated
100 µg/$924
HDAC6 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-HDAC6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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HDAC6 Mouse anti-Human Monoclonal (OTI3E7) Antibody
Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
HDAC6 Antibody - Anti-HDAC6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Cancer
HDAC6 Rabbit anti-Human Polyclonal (aa1166-1215) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$460
HDAC6 Antibody - Immunohistochemistry of HDAC6 in human testis tissue with HDAC6 antibody at 5 ug/ml.
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HDAC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
HDAC6 Antibody - Immunohistochemical analysis of Histone Deacetylase 6 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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HDAC6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
HDAC6 Antibody - Immunohistochemical analysis of Histone Deacetylase 6 (pS22) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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HDAC6 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
HDAC6 Antibody - 1:100 staining human Testis tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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HDAC6 Rabbit anti-Human Polyclonal (pSer22) Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HDAC6 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human testis tissue using HDAC6 (Phospho-Ser22) antibody.
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HDAC6 Rabbit anti-Human Polyclonal (pSer22) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
HDAC6 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human testis tissue using HDAC6 antibody.
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HDAC6 Rabbit anti-Human Polyclonal (Ab-22) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
HDAC6 Antibody - Western blot of HDAC6 phosphorylation expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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HDAC6 Rabbit anti-Human Polyclonal (pSer22) Antibody
Mouse, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
HDAC6 Antibody - Western blot of HDAC6 expression in HepG2 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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HDAC6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).