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Catalog Number Size Price
LS-B11730-100 100 µg (1 mg/ml) $485 
CD44 Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
CD44 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
CD44 Antibody - Flow cytometry of CD44 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
CD44 Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
CD44 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
CD44 Antibody - Flow cytometry of CD44 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
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PathPlus™ Monoclonal Mouse anti‑Human CD44 Antibody (clone BU52, Azide‑free, IHC) LS‑B11730

PathPlus™ Monoclonal Mouse anti‑Human CD44 Antibody (clone BU52, Azide‑free, IHC) LS‑B11730

Note: This antibody replaces LS-C134443
Antibody:
CD44 Mouse anti-Human Monoclonal (Azide-free) (BU52) Antibody
Application:
IHC, IHC-P, Flo
Reactivity:
Human
Format:
Unconjugated, Azide-free
Price
Catalog Number
$485
LS-B11730-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
CD44 Mouse anti-Human Monoclonal (Azide-free) (BU52) Antibody
Application:
IHC, IHC-P, Flo
Reactivity:
Human
Format:
Unconjugated, Azide-free

Specifications

Description
CD44 is a glycoprotein receptor that is involved in cell adhesion, cell migration, and other cell-cell interactions. It plays a role in many cellular functions including lymphocyte activation, recirculation, and homing, hematopoiesis, and the progression and metastasis of cancer cells. CD44 exists in several isoforms, and the main isoform is expressed ubiquitously in the cytoplasm and membrane of various cell types throughout the body in normal and diseased tissues including cancers and autoimmune diseases. The absence of the main isoform, or the presence of certain other isoforms in cancer cells, is associated with poor prognosis. In immunohistochemistry, CD44 is a marker for squamous epithelium, and in cancer it can distinguish reactive urothelium from carcinoma in situ. It is positive in colorectal cancer, glioma, oligodendroglioma, prostatic small cell carcinoma, squamous cell and adneosquamous carcinoma. Loss of CD44 is a general marker of poor prognosis in cancer. References: Front Cell Dev Biol. 2017;5:18. doi: 10.3389/fcell.2017.00018; Saudi Med J. 2015;36(3):273-279. doi: 10.15537/smj.2015.3.9622; Arch Immunol Ther Exp (Warsz). 2004;52(1):13-26. PMID: 15053229; Pathol Int. 2012;62(7):463-470. doi: 10.1111/j.1440-1827.2012.02823.x; Recent Pat Inflamm Allergy Drug Discov. 2017;11(2):77-91. doi: 10.2174/1872213X11666170907111858; Stem Cells Transl Med. 2015;4(9):1033-1043. doi: 10.5966/sctm.2015-0048.
Target
Human CD44
Synonyms
CD44 | CDW44 | CD44 antigen | Cell surface glycoprotein CD44 | CSPG8 | ECMR-III | Epican | HUTCH-I | LHR | MDU2 | MC56 | MIC4 | Hermes antigen | Hyaluronate receptor | Phagocytic glycoprotein 1 | PGP-1 | PGP-I | Pgp1 | Phagocytic glycoprotein I | MDU3 | CD44R | HCELL | Heparan sulfate proteoglycan
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
BU52
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Azide-free
Immunogen
Human peripheral myeloma cells
Specificity
Epitope 1 of the CD44 molecule.
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Flow Cytometry
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Presentation
50 mM Sodium Phosphate, pH 7.5, 150 mM NaCl, 100 mM KCl
Storage
Store at 4°C. Do not freeze. Open under aseptic conditions.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD44
P16070 NM_000610 NP_000601.3

Validation

CD44 Antibody - Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.

CD44 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE) This image was taken for the unmodified form of this product. Other forms have not been tested.

LSBio Ratings

PathPlus™ CD44 Antibody (clone BU52, Azide-free) for IHC, Flow LS-B11730 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 2/26/2024