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Catalog Number Size Price
LS-B14486-100 100 µl (2.93 mg/ml) $485 
CD44 Antibody - Human Spleen, germinal center lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
CD44 Antibody - Human Skin, epidermis: Formalin-Fixed, Paraffin-Embedded (FFPE)
CD44 Antibody - Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa using CD44 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.
CD44 Antibody - Sample (30 ug of whole cell lysate). A: A549, B: H1299, C: MCF-7. 10% SDS PAGE. CD44 antibody diluted at 1:10000.
CD44 Antibody - Human Spleen, germinal center lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
CD44 Antibody - Human Skin, epidermis: Formalin-Fixed, Paraffin-Embedded (FFPE)
CD44 Antibody - Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa using CD44 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.
CD44 Antibody - Sample (30 ug of whole cell lysate). A: A549, B: H1299, C: MCF-7. 10% SDS PAGE. CD44 antibody diluted at 1:10000.
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PathPlus™ Polyclonal Rabbit anti‑Human CD44 Antibody (aa1‑258, IHC, WB) LS‑B14486

PathPlus™ Polyclonal Rabbit anti‑Human CD44 Antibody (aa1‑258, IHC, WB) LS‑B14486

Note: This antibody replaces LS-C185465
Antibody:
CD44 Rabbit anti-Human Polyclonal (aa1-258) Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$485
LS-B14486-100
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
CD44 Rabbit anti-Human Polyclonal (aa1-258) Antibody
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
CD44 is a glycoprotein receptor that is involved in cell adhesion, cell migration, and other cell-cell interactions. It plays a role in many cellular functions including lymphocyte activation, recirculation, and homing, hematopoiesis, and the progression and metastasis of cancer cells. CD44 exists in several isoforms, and the main isoform is expressed ubiquitously in the cytoplasm and membrane of various cell types throughout the body in normal and diseased tissues including cancers and autoimmune diseases. The absence of the main isoform, or the presence of certain other isoforms in cancer cells, is associated with poor prognosis. In immunohistochemistry, CD44 is a marker for squamous epithelium, and in cancer it can distinguish reactive urothelium from carcinoma in situ. It is positive in colorectal cancer, glioma, oligodendroglioma, prostatic small cell carcinoma, squamous cell and adneosquamous carcinoma. Loss of CD44 is a general marker of poor prognosis in cancer. References: Front Cell Dev Biol. 2017;5:18. doi: 10.3389/fcell.2017.00018; Saudi Med J. 2015;36(3):273-279. doi: 10.15537/smj.2015.3.9622; Arch Immunol Ther Exp (Warsz). 2004;52(1):13-26. PMID: 15053229; Pathol Int. 2012;62(7):463-470. doi: 10.1111/j.1440-1827.2012.02823.x; Recent Pat Inflamm Allergy Drug Discov. 2017;11(2):77-91. doi: 10.2174/1872213X11666170907111858; Stem Cells Transl Med. 2015;4(9):1033-1043. doi: 10.5966/sctm.2015-0048.
Target
Human CD44
Synonyms
CD44 | CDW44 | CD44 antigen | Cell surface glycoprotein CD44 | CSPG8 | ECMR-III | Epican | HUTCH-I | LHR | MDU2 | MC56 | MIC4 | Hermes antigen | Hyaluronate receptor | Phagocytic glycoprotein 1 | PGP-1 | PGP-I | Pgp1 | Phagocytic glycoprotein I | MDU3 | CD44R | HCELL | Heparan sulfate proteoglycan
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Recombinant protein encompassing a sequence within the center region of human CD44. The exact sequence is proprietary.
Epitope
aa1-258
Specificity
human CD44
Applications
  • IHC
  • IHC - Paraffin (1:100 - 1:1000) & (5 µg/ml)
  • ICC (1:100 - 1:1000)
  • Western blot (1:5000 - 1:20000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).
Presentation
1X PBS, pH 7, 0.025% ProClin™ 300, 20% Glycerol
Storage
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD44
P16070 NM_000610 NP_000601.3

Validation

CD44 Antibody - Human Spleen, germinal center lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen, germinal center lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen, germinal center lymphocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)

CD44 Antibody - Human Skin, epidermis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin, epidermis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Skin, epidermis: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ CD44 Antibody (aa1-258) for IHC, ICC, WB/Western LS-B14486 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 2/26/2024