A synthetic peptide corresponding to amino acids 241-260 (DAVSSDRNFPNSTNLPRNP) from the BIR3 domain of human XIAP, GenBank no. NP_001158.2. Percent identity by BLAST analysis: Human, Gorilla (100%); Gibbon (95%); Monkey, Marmoset, Panda, Rabbit, Horse, Pig (89%); Mouse, Rat, Elephant (84%).
recognizes epitopes in the BIR2 domain of XIAP. Therefore it can recognize full-length XIAP and XIAP cleavage fragments containing the BIR2 domain. However, XIAP cleavage fragments may be biologically unstable, and therefore cleavage fragments may be difficult to detect.
Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
This antibody carries the LSBio 100% Guarantee.