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| Catalog Number | Size | Price |
|---|---|---|
| LS-C500509-50 | 50 µg | $294 |
| LS-C500509-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human Tuberin / TSC2 Antibody (IF, WB) LS‑C500509
Polyclonal Rabbit anti‑Human Tuberin / TSC2 Antibody (IF, WB) LS‑C500509
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
TSC2 antibody LS-C500509 is an unconjugated rabbit polyclonal antibody to TSC2 (Tuberin) from human. It is reactive with human and mouse. Validated for ELISA, IF and WB.
Target
Human Tuberin / TSC2
Synonyms
TSC2 | LAM | Tuberous sclerosis 2 protein | TSC4 | Tuberin | Tuberous sclerosis 2
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant human Tuberin protein (1396-1496AA)
Specificity
In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.
Applications
- Immunofluorescence
- Western blot
- ELISA
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About Tuberin / TSC2
Publications (0)
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, ELISA
Species:
Mouse, Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human
Applications:
Immunofluorescence, Dot Blot
Species:
Human, Monkey, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/28/2024
Date Requested: 4/28/2024
