Cardiac Troponin I antibody LS-C188639 is an unconjugated mouse monoclonal antibody to human Cardiac Troponin I (TNNI3). Validated for ELISA, IP and WB.
Human TNNI3 / Cardiac Troponin I
(tested or 100% immunogen sequence identity)
Protein A purified
- Western blot
Mixture of free human cardiac Troponin I and native human cardiac Troponin complex.
Recognizes human cardiac Troponin I (cTnI). Troponin I is a 24kD subunit of Troponin, a protein found on muscle tissue responsible for muscle contraction. When calcium binds to Troponin C, a conformational change moves Troponin I and tropomyosin out of the way of the myosin binding sites on the actin filaments in muscles. This allows cross-bridging to occur and the muscle to contract. Levels of cTnI in serum are commonly used as a marker for cardiac cell damage and death. The antibody recognizes an epitope between amino acid residues 169 - 178 and does not cross react with skeletal TnI.
PBS, 0.09% Sodium Azide
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
For research use only.
About TNNI3 / Cardiac Troponin I