Recombinant Monoclonal Mouse anti‑Human MCAM / CD146 Antibody (clone rMUC18/1130, Azide‑free,Carrier‑free, IHC) LS‑C751265
Recombinant Monoclonal Mouse anti‑Human MCAM / CD146 Antibody (clone rMUC18/1130, Azide‑free,Carrier‑free, IHC) LS‑C751265
Antibody:
MCAM / CD146 Mouse anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (rMUC18/1130) Antibody
Format:
Unconjugated, Azide-free, Carrier-free
Overview
Antibody:
MCAM / CD146 Mouse anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (rMUC18/1130) Antibody
Format:
Unconjugated, Azide-free, Carrier-free
Specifications
Description
CD146 antibody LS-C751265 is an unconjugated mouse recombinant monoclonal antibody to human CD146 (MCAM). Validated for IHC.
Target
Human MCAM / CD146
Synonyms
MCAM | CD146 | CD146 antigen | Gicerin | Melanoma adhesion molecule | MUC18 | p1h12
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Recombinant Monoclonal
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Azide-free, Carrier-free.
Also available
Unmodified.
Immunogen
Recombinant full-length human MUC18 protein. Antigen Molecular Weight: 130 kDa
Specificity
Mel-CAM belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Applications
- IHC - Paraffin (0.5 - 1 µg/ml)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Usage
Immunohistology (Formalin-fixed - 0.5-1.0 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
Featured Products
Species:
Rat
Applications:
Western blot, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, Western blot, ELISA
Species:
Mouse
Applications:
Western blot, ELISA
Species:
Human, Mouse, Dog, Rabbit
Applications:
IHC, ICC, Immunoprecipitation, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/3/2024