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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LMNA / Lamin A+C Antibody (aa550‑600) LS‑C290111
Lamin A+C antibody LS-C290111 is an unconjugated rabbit polyclonal antibody to Lamin A+C (LMNA) from human, mouse, rat and other species. Validated for IF, IHC, IP and WB.
Catalog
Size
Price
LS-C290111-100
100 µl (0.2 mg/ml)
$395

Popular LMNA / Lamin A+C Products

Anti-Lamin A/C antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2005 dilution 1:50.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Anti-Lamin A/C antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B119 dilution 1:100.
Species: Human, Monkey, Mouse, Rat, Dog, Hamster, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin, Western blot
Lamin expression in basal cell skin carcinomas. Frozen sections stained with Lamin A antibody [JOL4]
Species: Human, Mouse
Applications: IHC, IHC - Frozen, Immunofluorescence, Western blot, Immunoprecipitation
Anti-Lamin A/C antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2973 dilution 1:100.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, Flow Cytometry
Antibody
Species: Xenopus, Human, Mouse, Rat, Bovine
Applications: IHC, IHC - Frozen, Immunofluorescence, Western blot

Product Description

Lamin A+C antibody LS-C290111 is an unconjugated rabbit polyclonal antibody to Lamin A+C (LMNA) from human, mouse, rat and other species. Validated for IF, IHC, IP and WB.
About LMNA / Lamin A+C
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. P02545 NM_005572 NP_005563.1

LMNA Antibody, 70 kDa lamin Antibody, CDCD1 Antibody, CMD1A Antibody, EMD2 Antibody, FPLD Antibody, IDC Antibody, FPL Antibody, FPLD2 Antibody, Lamin A/C Antibody, Lamin Antibody, LFP Antibody, LMNC Antibody, LMN1 Antibody, LMNL1 Antibody, HGPS Antibody, Prelamin-A/C Antibody, PRO1 Antibody, Lamin A Antibody, Lamin A/C-like 1 Antibody, LGMD1B Antibody, CDDC Antibody, CMT2B1 Antibody, LDP1 Antibody


Specifications

Target
Human LMNA / Lamin A+C
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:200 - 1:1000)
  • Immunofluorescence (1:100 - 1:500)
  • Western blot (1:2000 - 1:10000)
  • Immunoprecipitation (2 - 10 µg/mg lysate)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Epitope
aa550-600
Specificity
Region between residue 550 and 600 of human Lamin A using the numbering given in entry NP_733821.1 (GeneID 4000).
Usage
Immunohistochemistry: Antigen retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Human controls: Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Osteosarcoma, Ovarian Carcinoma, Stomach Adenocarcinoma, Testicular Seminoma.
Manufacturer
Bethyl Laboratories, Inc.
Presentation
TBS, 0.09% Sodium Azide, 0.1% BSA
Storage
Store at 2°C to 8°C for up to 1 year.
Restrictions
For research use only.

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Images

Immunohistochemistry

Detection of Mouse Lamin-A by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Detection of Mouse Lamin-A by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Immunohistochemistry

Detection of Human Lamin-A by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.
Detection of Human Lamin-A by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.

Immunohistochemistry

Detection of Mouse Lamin-A by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Detection of Mouse Lamin-A by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Immunohistochemistry

Detection of Human Lamin-A by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.
Detection of Human Lamin-A by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.

Immunohistochemistry

Detection of Mouse Lamin-A by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Detection of Mouse Lamin-A by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Immunohistochemistry

Detection of Human Lamin-A by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.
Detection of Human Lamin-A by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.

Immunohistochemistry

Detection of Mouse Lamin-A by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:200 (1 ug/ml). Detection: DAB.
Detection of Mouse Lamin-A by Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Immunohistochemistry

Detection of Human Lamin-A by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.
Detection of Human Lamin-A by Immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-Lamin-A used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.

Requested From: United States
Date Requested: 9/19/2018

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