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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IRF3 Antibody LS‑C122005
IRF3 antibody LS-C122005 is an unconjugated rabbit polyclonal antibody to human IRF3. Validated for IHC and WB.
Antibody
Catalog
Size
Price
LS-C122005-50
50 µg
$890

Popular IRF3 Products

Anti-IRF3 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B182 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Immunofluorescent staining using IRF3 antibody. Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were stained with anti-IRF3 antibody.
Species: Human
Applications: ICC, Western blot, Immunoprecipitation, Flow Cytometry, Dot Blot
Anti-IRF3 Antibody (phospho-Ser396) antibody at 1:500 dilution with Jurkat cells treated with 200 ng/ml of EGF for 30 minutes.
Species: Human, Mouse, Rat
Applications: Western blot, ELISA
Anti-IRF3 antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2529 dilution 1:50.
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: Western blot, ELISA

Product Description

IRF3 antibody LS-C122005 is an unconjugated rabbit polyclonal antibody to human IRF3. Validated for IHC and WB.
About IRF3
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Q14653 NM_001571 NP_001562.1

IRF3 Antibody, Interferon regulatory factor 3 Antibody, IRF-3 Antibody


Specifications

Target
Human IRF3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
IRF3 antibody was raised against synthetic peptide corresponding to a 14 amino acid sequence near the centre of human IRF3.
Specificity
Recognizes human IRF3.
Usage
Suitable for use in Immunohistochemistry (paraffin) and Western Blot. Immunohistochemistry (paraffin): 5 ug/ml. Western Blot: 2 ug/ml.
Presentation
PBS, 0.02% Sodium Azide
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for up to 1 year.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/21/2018

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