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IL11

interleukin 11

Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

Gene Name: interleukin 11
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: IL11, AGIF, Adipogenesis inhibitory factor, IL-11, Interleukin-11, Interleukin 11
Target Sequences: NM_000641 NP_000632.1 P20809

Publications (1)

1
Interleukin-11-expressing fibroblasts have a unique gene signature correlated with poor prognosis of colorectal cancer10<sup> Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA12<sup> Department of Immunology, Juntendo University Graduate School of Medicine, Tokyo, Japan14<sup> Department of Pathology, Toho University School of Medicine, Tokyo, Japan16<sup> Host Defense Research Center, Toho University School of Medicine, Tokyo, Japan. hiroyasu.nakano@med.toho-u.a. Takashi Nishina, Yutaka Deguchi, Daisuke Ohshima, Wakami Takeda , Masato Ohtsuka , Shigeyuki Shichino, Satoshi Ueha, Soh Yamazaki, Mika Kawauchi, Eri Nakamura, Chiharu Nishiyama, Yuko Kojima, Satomi Adachi-Akahane, Mizuho Hasegawa, Mizuho Nakayama, Masanobu Oshima, Hideo Yagita, Kazutoshi Shibuya, Tetuo Mikami, Naohiro Inohara, Kouji Matsushima, Norihiro Tada, Hiroyasu Nakano. Nature communications. 2021 Apr;12:2281. [Full Text Article] [PubMed:33863879] [PMC:PMC8052408] Related Antibodies: LS-C408373.

☰ Filters
Antibodies (50)
ELISA Kits (33)
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IL11 (106)
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IL11 Antibody - Human Skin, Dermal Capillaries: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL11 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
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IL11 Rabbit anti-Human Polyclonal (aa22-199) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$389
IL11 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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IL11 Rabbit anti-Human Polyclonal (aa22-199) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
IL11 Antibody - Western Blot (reducing) of IL-11 antibody
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IL11 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
500 µg/$326
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IL11 Rabbit anti-Human Polyclonal (N-Terminal) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µl/$289; 100 µl/$319; 200 µl/$389
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IL11 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Func, Neut
Unconjugated
500 µg/$508
IL11 Antibody - Anti-Human IL-11 Western Blot Reduced
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IL11 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$356; 100 µg/$396
IL11 Antibody - Biotinylated Anti-Human IL-11 Western Blot Reduced
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IL11 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
IL11 Antibody - Western Blot of IL11 antibody.
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IL11 Mouse anti-Human Monoclonal (KT8) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$437
IL11 Antibody - IHC of IL-11 (G27) pAb in paraffin-embedded human pancreas tissue.
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IL11 Rabbit anti-Human Polyclonal (Gly27) Antibody
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
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IL11 Mouse anti-Human Monoclonal (3C6) Antibody
Human
ELISA
Unconjugated
100 µg/$423
IL11 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
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E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
19.3 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$282; 10 µg/$370
IL11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
IL11 ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
IL11 Protein - Eukaryotic Interleukin 11 (IL11) by SDS-PAGE
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293F Cells
His, N-Terminal
24kDa
10 µg/$283; 50 µg/$457; 200 µg/$912; 1 mg/$2,032; 5 mg/$3,193; 2 mg/$2,219
IL11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
IL11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.0156 - 1 mg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
IL11 Antibody - IHC analysis of IL-11 antibody in paraffin-embedded human pancreas tissue.
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IL11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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IL11 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
50 µg/$305; 100 µg/$357
IL11 Antibody - Western blot of recombinant IL11.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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IL11 Rabbit anti-Human Polyclonal (aa22-199) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
IL11 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
~23 kDa (SDS-PAGE)
5 µg/$296; 25 µg/$478; 1 mg/$3,661
Select
IL11 Mouse anti-Human Monoclonal (aa25-74) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Viewing 1-25 of 106 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).