LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
IL11 Antibody LS‑C104366
Note: This antibody replaces LS-C8131, LS-C54085
IL11 antibody LS-C104366 is an unconjugated rabbit polyclonal antibody to human IL11. Validated for ELISA, Neut and WB.
Catalog
Size
Price
LS-C104366-50
50 µg
$285
LS-C104366-100
100 µg
$325

Popular IL11 Products

Antibody
Species: Human
Applications: ELISA, Functional Assay, Neutralization
Western Blot (non-reducing) of IL-11 antibody LS-C104441
Species: Human
Applications: Western blot, ELISA
IHC of IL-11 (G27) pAb in paraffin-embedded human pancreas tissue.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin
Human Uterus, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human
Applications: IHC, IHC - Paraffin, ICC, Western blot, ELISA

Product Description

IL11 antibody LS-C104366 is an unconjugated rabbit polyclonal antibody to human IL11. Validated for ELISA, Neut and WB.
About IL11
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). P20809 NM_000641 NP_000632.1

IL11 Antibody, AGIF Antibody, Adipogenesis inhibitory factor Antibody, IL-11 Antibody, Interleukin-11 Antibody, Oprelvekin Antibody, Interleukin 11 Antibody


Specifications

Target
Human IL11
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • ELISA (0.5 - 2 µg/ml)
  • Neutralization (0.15 - 0.25 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
IL11 antibody was raised against e.coli derived recombinant Human IL-11.
Specificity
Human IL-11
Usage
Immunohistochemistry: This antibody stained human brain stroke (including control cortex and stroke core areas) tissue. The primary antibody was incubated at 2.5 mg/ml overnight at 4°C. This was followed by a fluorophore conjugated secondary antibody. Optimal concentrations and conditions may vary. Information and photo are courtesy of the Tissue Profiling group, SciLifeLab Stockholm. Neutralization: To yield one-half maximal inhibition [ND] of the biological activity of hIL-11 (1.50 ng/ml), a concentration of 0.02-0.05 ug/ml of this antibody is required. ELISA: To detect hIL-11 by sandwich ELISA (using 100 ul/well antibody solution) a concentration of 0.5-2 ug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human IL-11 (LS-C104365) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant hIL-11. Western Blot: To detect hIL-11 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-11 is 1.5-3 ng/lane, under either reducing or non-reducing conditions.
Presentation
Lyophilized from PBS, pH 7.2
Reconstitution
Sterile water
Storage
Store Lyophilized at room temperature up to 1 month; Reconstituted for up to 2 weeks at 2°C to 8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images

Enzyme-Linked Immunosorbent Assay

Sandwich ELISA of IL-11 antibody LS-C104366.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Sandwich ELISA of IL-11 antibody LS-C104366. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Enzyme-Linked Immunosorbent Assay

Sandwich ELISA of IL-11 antibody LS-C104366.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Sandwich ELISA of IL-11 antibody LS-C104366. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Enzyme-Linked Immunosorbent Assay

Sandwich ELISA of IL-11 antibody LS-C104366.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Sandwich ELISA of IL-11 antibody LS-C104366. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Enzyme-Linked Immunosorbent Assay

Sandwich ELISA of IL-11 antibody LS-C104366.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Sandwich ELISA of IL-11 antibody LS-C104366. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 7/21/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number