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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IGF2R / CD222 Antibody (AP) LS‑C506843
CD222 antibody LS-C506843 is an AP-conjugated mouse monoclonal antibody to CD222 (IGF2R) from human, mouse and monkey.
Antibody
Catalog
Size
Price
LS-C506843-100
100 µl
$965

Popular IGF2R / CD222 Products

Antibody
Species: Human, Primate
Applications: Flow Cytometry
Permeabilized Peripheral Human Granulocytes stained with Mouse anti Human CD222: APC. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Rhesus monkey
Applications: Flow Cytometry
Anti-IGF2R antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5653 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemical analysis of CD222 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Bovine
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, ELISA

Product Description

CD222 antibody LS-C506843 is an AP-conjugated mouse monoclonal antibody to CD222 (IGF2R) from human, mouse and monkey.
About IGF2R / CD222
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. P11717 NM_000876 NP_000867.2

IGF2R Antibody, CD222 antigen Antibody, CIMPR Antibody, CI Man-6-P receptor Antibody, CI-MPR Antibody, IGF-II receptor Antibody, MPR 300 Antibody, MPR1 Antibody, MPRI Antibody, M6P-R Antibody, M6P/IGF2R Antibody, CD222 Antibody, M6P/IGF2 receptor Antibody


Specifications

Target
Human IGF2R / CD222
Host
Mouse
Reactivity
Human, Monkey, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Alkaline Phosphatase. Also available Unconjugated or conjugated with Biotin, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
IGF2R / CD222 antibody was raised against recombinant vaccinia virus containing CD222.
Specificity
Recognizes human and mouse CD222. Recognizes an epitope located in the region between extracellular domains 2 and 5 (aa 192-697; UniProt Accession #P11717) of CD222 (Roberts, et al.). Species Cross-reactivity: Rhesus monkey
Presentation
PBS, pH 7.2
Storage
Store at 4°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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