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| Catalog Number | Size | Price |
|---|---|---|
| LS-C501529-50 | 50 µg | $294 |
| LS-C501529-100 | 100 µg | $360 |
1 of 2
2 of 2
Polyclonal Rabbit anti‑Human Hamartin / TSC1 Antibody (IHC, IF) LS‑C501529
Polyclonal Rabbit anti‑Human Hamartin / TSC1 Antibody (IHC, IF) LS‑C501529
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
TSC1 antibody LS-C501529 is an unconjugated rabbit polyclonal antibody to human TSC1 (Hamartin). Validated for ELISA, IF and IHC.
Target
Human Hamartin / TSC1
Synonyms
TSC1 | LAM | Tuberous sclerosis 1 protein | Tuberous sclerosis 1 | Hamartin | KIAA0243 | TSC | Tumor suppressor
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant human Hamartin protein (101-344AA)
Specificity
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
Applications
- IHC
- Immunofluorescence
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About Hamartin / TSC1
Publications (0)
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Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human, Mouse
Applications:
Western blot, Immunoprecipitation
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/30/2024
Date Requested: 4/30/2024
