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GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
Gene Name: | gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
Family/Subfamily: | Ion Channel , GABA A receptor |
Synonyms: | GABRA5, Alpha 5, GABA A receptor alpha 5 |
Target Sequences: | NM_000810 NP_000801.1 P31644 |
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