GPR40 antibody LS-C146689 is an unconjugated rabbit polyclonal antibody to human GPR40 (FFAR1). Validated for IHC.
Human FFAR1 / GPR40
(tested or 100% immunogen sequence identity)
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FFAR1 / GPR40 antibody was raised against human GPR40 amino acids 210-222
GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes. The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7. GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.
TBS, pH 7.4, 0.5 mg/ml BSA, 0.02% Sodium Azide, 50% Glycerol
Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.
For research use only.