Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-A1599-50 50 µg (1 mg/ml) $440 
FFAR1 / GPR40 Antibody - Brain, Glioblastoma
FFAR1 / GPR40 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
FFAR1 / GPR40 Antibody - Anti-GPR40 antibody IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
FFAR1 / GPR40 Antibody - Brain, Glioblastoma
FFAR1 / GPR40 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
FFAR1 / GPR40 Antibody - Anti-GPR40 antibody IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
1 of 3
2 of 3
3 of 3

PathPlus™ Polyclonal Rabbit anti‑Human FFAR1 / GPR40 Antibody (Cytoplasmic Domain, IHC) LS‑A1599

PathPlus™ Polyclonal Rabbit anti‑Human FFAR1 / GPR40 Antibody (Cytoplasmic Domain, IHC) LS‑A1599

Antibody:
FFAR1 / GPR40 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-A1599-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
FFAR1 / GPR40 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Format:
Unconjugated, Unmodified

Specifications

Description
Free fatty acid receptor 1 (FFAR1) is a G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. FFAR1 increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). FFAR1 plays a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human FFAR1 / GPR40
Synonyms
FFAR1 | FFAR | FFA1R | G protein-coupled receptor 40 | GPCR40 | GPR40 | Free fatty acid receptor | Free fatty acid receptor 1 | G-protein coupled receptor 40
Host
Rabbit
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from 1st cytoplasmic domain of human GPR40. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (95%); Mouse, Hamster, Pig (84%).
Epitope
Cytoplasmic Domain
Specificity
Human GPR40. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (5 - 10 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About FFAR1 / GPR40
O14842 NM_005303 NP_005294.1

Validation

FFAR1 / GPR40 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

FFAR1 / GPR40 Antibody - Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

FFAR1 / GPR40 Antibody - Anti-GPR40 antibody IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR40 antibody IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR40 antibody IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ FFAR1 / GPR40 Antibody (Cytoplasmic Domain) for IHC LS-A1599 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/5/2024