Recombinant Monoclonal Rabbit anti‑Human ER Alpha / Estrogen Receptor Antibody (clone ESR1/2299R, Azide‑free,Carrier‑free, IHC, WB) LS‑C751131
Recombinant Monoclonal Rabbit anti‑Human ER Alpha / Estrogen Receptor Antibody (clone ESR1/2299R, Azide‑free,Carrier‑free, IHC, WB) LS‑C751131
Antibody:
ER Alpha / Estrogen Receptor Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (ESR1/2299R) Antibody
Format:
Unconjugated, Azide-free, Carrier-free
Overview
Antibody:
ER Alpha / Estrogen Receptor Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (ESR1/2299R) Antibody
Format:
Unconjugated, Azide-free, Carrier-free
Specifications
Description
Estrogen Receptor antibody LS-C751131 is an unconjugated rabbit recombinant monoclonal antibody to human Estrogen Receptor (ER Alpha). Validated for IHC and WB.
Target
Human ER Alpha / Estrogen Receptor
Synonyms
ESR1 | Era | ERalpha | Estrogen receptor | ER-alpha | Estrogen receptor 1 | NR3A1 | ER | ESR | ESRA | Estrogen receptor alpha
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Recombinant Monoclonal
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Azide-free, Carrier-free.
Also available
Unmodified.
Immunogen
Recombinant full-length human Estrogen Receptor alpha protein. Antigen Molecular Weight: ~67 kDa
Specificity
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.
Applications
- IHC - Paraffin (1 - 2 µg/ml)
- Western blot (0.5 - 2 µg/ml)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Usage
Western Blot (0.5-2 ug/ml) - Immunohistology (Formalin-fixed - 1-2 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ER Alpha / Estrogen Receptor
Featured Products
Species:
Bovine, Human, Mouse
Applications:
IHC, IHC - Frozen, Western blot, Immunoprecipitation
Species:
Human, Mouse
Applications:
IHC, Western blot, Immunoprecipitation, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, ICC, Western blot, Immunoprecipitation, Gel shift
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/29/2024