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Catalog Number Size Price
LS-C357865-20 20 µg (0.2 mg/ml) $347 
LS-C357865-100 100 µg (0.2 mg/ml) $522 
EGFR Antibody - Western blot testing of A431 lysate using EGFR antibody at 1ug/ml.

Monoclonal Mouse anti‑Human EGFR Antibody (clone H9B4, WB) LS‑C357865

Monoclonal Mouse anti‑Human EGFR Antibody (clone H9B4, WB) LS‑C357865

Antibody:
EGFR Mouse anti-Human Monoclonal (H9B4) Antibody
Application:
WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$347
LS-C357865-20
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
EGFR Mouse anti-Human Monoclonal (H9B4) Antibody
Application:
WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
EGFR antibody LS-C357865 is an unconjugated mouse monoclonal antibody to human EGFR. Validated for ELISA, IP and WB.
Target
Human EGFR
Synonyms
EGFR | EGF Receptor | ERBB | ERBB1 | MENA | PIG61 | Proto-oncogene c-ErbB-1 | V-erb-b homolog | EGF-R | HER1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat
Clonality
IgG1 Monoclonal
Clone
H9B4
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified. Also available Azide-free, BSA-free.
Immunogen
Purified EGFR from A431 cells.
Specificity
Human EGFR
Applications
  • Western blot (0.5 - 1 µg/ml)
  • Immunoprecipitation
  • ELISA
Usage
Epidermal Growth Factor Receptor is a type I receptor tyrosine kinase, referred to as&nbsp.<a href=../search_result.php?search_txt=egfr>EGFR</a>, ErbB1 and HER1. When EGFR is activated by one of its ligands, it dimerizes. It can form a homodimer, heterodimers with other ErbB family members, or even a cluster of EGFRs. Activation stimulates EGFRs intracellular kinase activity. Autophosphorylation of tyrosine residues in the C-terminal domain of EGFR leads to association with proteins with phosphotyrosine-binding domains which then signal the initiation of signal transduction cascades including the JNK, MAPK, AKT, and possibly&nbsp.<a href=../apoptosis-antibodies.html>Nf-KB</a>, pathways. Overexpression of EGFR is the cause of some types of cancer, including lung and colon cancer. It has also been linked to psoriasis, eczema and atherosclerosis, although poorly defined. Monoclonal antibody to EGFR can be used to block the extracellular ligand binding domain, therebye blocking tyrosine kinase activation and subsequent signal transduction. ELISA: Order BSA-free antibody format for coating.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About EGFR
P00533 NM_005228 NP_005219.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/4/2021