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Catalog Number Size Price
LS-C388096-20 20 µg (0.2 mg/ml) $347 
LS-C388096-100 100 µg (0.2 mg/ml) $522 
CTNNB1 / Beta Catenin Antibody - Formalin/paraffin breast lobular carcinoma stained with beta-Catenin p120 antibody. Note cytoplasmic staining in lobular carcinoma.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CTNNB1 / Beta Catenin Antibody - Formalin/paraffin breast ductal carcinoma stained with beta-Catenin antibody. Note membrane staining in ductal carcinoma.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CTNNB1 / Beta Catenin Antibody - Western blot testing of human and mouse samples using beta-Catenin antibody.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CTNNB1 / Beta Catenin Antibody - Formalin/paraffin breast lobular carcinoma stained with beta-Catenin p120 antibody. Note cytoplasmic staining in lobular carcinoma.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CTNNB1 / Beta Catenin Antibody - Formalin/paraffin breast ductal carcinoma stained with beta-Catenin antibody. Note membrane staining in ductal carcinoma.  This image was taken for the unmodified form of this product. Other forms have not been tested.
CTNNB1 / Beta Catenin Antibody - Western blot testing of human and mouse samples using beta-Catenin antibody.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Polyclonal Rabbit anti‑Human CTNNB1 / Beta Catenin Antibody (IHC, IF, WB) LS‑C388096

Polyclonal Rabbit anti‑Human CTNNB1 / Beta Catenin Antibody (IHC, IF, WB) LS‑C388096

Antibody:
CTNNB1 / Beta Catenin Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$347
LS-C388096-20
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CTNNB1 / Beta Catenin Rabbit anti-Human Polyclonal Antibody
Application:
IHC, IHC-P, IF, WB, IP, Flo
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
Beta Catenin antibody LS-C388096 is an unconjugated rabbit polyclonal antibody to Beta Catenin (CTNNB1) from human. It is reactive with human and mouse. Validated for Flow, IF, IHC, IP and WB.
Target
Human CTNNB1 / Beta Catenin
Synonyms
CTNNB1 | Beta-catenin | Catenin beta-1 | CTNNB | Beta Catenin
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified. Also available Ready-to-Use, Azide-free, BSA-free.
Immunogen
Synthetic peptide from the middle of beta-Catenin / p120 protein.
Specificity
Human CTNNB1 / Beta Catenin
Applications
  • IHC
  • IHC - Paraffin (1 - 2 µg/ml)
  • Immunofluorescence (1 - 2 µg/ml)
  • Western blot (0.5 - 1 µg/ml)
  • Immunoprecipitation
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, it is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution throughout the cytoplasm results in a diffuse cytoplasmic pattern. Staining with beta-catenin antibody and E-cadherin antibody helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas. Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CTNNB1 / Beta Catenin
P35222 NM_001904 NP_001895.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 12/4/2021