Complement Factor B antibody LS-C44996 is an unconjugated mouse monoclonal antibody to human Complement Factor B (CFB). Validated for ELISA, Flow, Func, IHC and WB.
Human CFB / Complement Factor B
(tested or 100% immunogen sequence identity)
Protein A purified
- IHC - Frozen
- Western blot
- Flow Cytometry
- Functional Assay
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Purified human complement factor b.
Recognizes the 30kD Ba fragment of 90kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kD Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes. Binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
ELISA: LS-C44996 binds both the Ba fragment and the whole protein so is not suitable for all ELISA applications.
Borate buffered saline, pH 8.2 - 8.4, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
For research use only.
About CFB / Complement Factor B