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CFB / Complement Factor B

complement factor B

CFB / Complement Factor B is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Gene Name: complement factor B
Family/Subfamily: Protease , Serine S1
Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B
Target Sequences: NM_001710 NP_001701.2 P00751

☰ Filters
Products
Antibodies (140)
Primary (140)
CFB / Complement Factor B (140)
Human (85)
Mouse (46)
Rat (48)
Bovine (1)
IHC (28)
IHC-Fr (4)
IHC-P (11)
WB (132)
Flo (18)
ELISA (38)
Func (1)
ICC (10)
ID (1)
IF (2)
IP (8)
Peptide-ELISA (2)
rabbit (106)
mouse (33)
goat (1)
Product Group
IHCPlus (4)
IgG (35)
IgG1 (14)
IgG1 + IgG2b (1)
IgG2a (6)
IgG2b (2)
monoclonal mc (33)
polyclonal pc (107)
014III-33.2.4.3 (1)
032B-22.1.X (1)
10-09 (1)
APC (10)
APC Conjugated (11)
Azide-free (1)
Biotin Conjugated (19)
Cy3 Conjugated (10)
Cy7 Conjugated (10)
FITC Conjugated (19)
HRP Conjugated (16)
PE Conjugated (14)
Unconjugated (41)
aa270-388 (18)
aa34-159 (18)
aa35-160 (10)
aa269-382 (8)
aa32-157 (8)
aa474-590 (8)
aa476-592 (8)
aa477-600 (8)
aa469-494 (7)
N-Terminus (2)
210-290 aa, Internal (1)
Cleaved-Lys260 (1)
Internal (1)
aa23-761 (1)
aa241-290 (1)
aa26-764 (1)
aa395-422 (1)
No (140)
CFB / Complement Factor B Antibody - Anti-CFB / Factor B antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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CFB / Complement Factor B Goat anti-Human Polyclonal Antibody
Human
ID, IHC, IHC-P
Unconjugated
1 ml/$485
CFB / Complement Factor B Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa23-761) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CFB / Complement Factor B Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
CFB / Complement Factor B Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
CFB / Complement Factor B Antibody - Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
CFB / Complement Factor B Antibody - Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa474-590) (Biotin) Antibody
Mouse, Rat
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
CFB / Complement Factor B Antibody - Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Mouse Polyclonal (aa32-157) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571
CFB / Complement Factor B Antibody - Immunohistochemistry of paraffin-embedded mouse kidney using CFB antibodyat dilution of 1:200 (40x lens).
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CFB / Complement Factor B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CFB / Complement Factor B Antibody - Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa241-290) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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CFB / Complement Factor B Mouse anti-Human Monoclonal (N-Terminus) (014III-33.2.4.3) Antibody
Human
ELISA, Flo, IHC, IHC-Fr, WB
Unconjugated
0.1 ml/$568
CFB / Complement Factor B Antibody - Human Small Intestine, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa35-160) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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CFB / Complement Factor B Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
CFB / Complement Factor B Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal (aa270-388) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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CFB / Complement Factor B Mouse anti-Human Monoclonal (aa26-764) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$884
CFB / Complement Factor B Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CFB / Complement Factor B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CFB / Complement Factor B Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, WB
Unconjugated
100 µg/$794
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CFB / Complement Factor B Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated
100 µl/$1,022
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CFB / Complement Factor B Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
100 µl/$1,022
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CFB / Complement Factor B Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
100 µl/$1,022
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CFB / Complement Factor B Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, Func, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$872
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CFB / Complement Factor B Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated
100 µl/$1,063
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CFB / Complement Factor B Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
100 µl/$1,063
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CFB / Complement Factor B Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
100 µl/$1,063
CFB / Complement Factor B Antibody - Immunohistochemistry of paraffin-embedded Human mammary cancer using Complement Factor B Polyclonal Antibody at dilution of 1:200 (40x lens).
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CFB / Complement Factor B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CFB / Complement Factor B Antibody - Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CFB / Complement Factor B Rabbit anti-Rat Polyclonal (aa34-159) Antibody
Mouse, Rat
WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
Viewing 1-25 of 140 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).