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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CFB / Complement Factor B Antibody (aa241‑290) LS‑C121072
Complement Factor B antibody LS-C121072 is an unconjugated rabbit polyclonal antibody to Complement Factor B (CFB) from human and mouse. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C121072-50
50 µl (1 mg/ml)
$265
LS-C121072-100
100 µl (1 mg/ml)
$325

Popular CFB / Complement Factor B Products

Anti-CFB / Factor B antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7934 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Immunodiffusion
Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Rat
Applications: IHC, Western blot
Western blot of recombinant CFB / Complement Factor B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: IHC, Western blot
Antibody
Species: Human
Applications: Western blot, ELISA
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

Complement Factor B antibody LS-C121072 is an unconjugated rabbit polyclonal antibody to Complement Factor B (CFB) from human and mouse. Validated for Peptide-ELISA and WB.
About CFB / Complement Factor B
CFB / Complement Factor B is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. P00751 NM_001710 NP_001701.2

CFB Antibody, AHUS4 Antibody, B-factor, properdin Antibody, C3/C5 convertase Antibody, CFAB Antibody, C3 proaccelerator Antibody, C3 proactivator Antibody, Complement factor B Antibody, Complement protein Factor B Antibody, Glycine-rich beta-glycoprotein Antibody, GBG Antibody, Factor B Antibody, FB Antibody, Glycine-rich beta glycoprotein Antibody, PBF2 Antibody, BF Antibody, BFD Antibody, FBI12 Antibody, H2-Bf Antibody, Properdin factor B Antibody


Specifications

Target
Human CFB / Complement Factor B
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:20000)
Immunogen
Synthetic peptide from human CFAB Bb. (AA Range: 241-290)
Epitope
aa241-290
Specificity
CFAB Bb (Cleaved-Lys260) Antibody detects endogenous levels of fragment of activated CFAB Bb resulting from cleavage adjacent to Lys260.
Usage
Western Blot: Predicted MW 57 and 85 kDa
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from K562 cells, treated with etoposide 25 uM 1h, using CFAB Bb (Cleaved-Lys260) Antibody. The lane on the right is treated with the synthesized peptide.

Requested From: United States
Date Requested: 8/18/2018

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