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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CD300A Antibody (clone P192, RPE) LS-C187548

Human peripheral blood monocytes stained with Mouse anti-Human CD300a:RPE This image was taken for the unconjugated form of this product. Other forms have not been tested.

CD300A Antibody (clone P192, RPE) LS-C187548

Antibody:
Mouse Monoclonal to Human CD300A
Application:
Flo
Reactivity:
Human
Format:
R. Phycoerythrin, Unmodified
Price
Catalog Number
$515 
LS-C187548-100
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human CD300A
Application:
Flo
Reactivity:
Human
Format:
R. Phycoerythrin, Unmodified

Specifications

Description
CD300A antibody LS-C187548 is an RPE-conjugated mouse monoclonal antibody to human CD300A. Validated for Flow.

Target
Human CD300A
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Clone
P192
Conjugations
R. Phycoerythrin
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry
Immunogen
CD300A antibody was raised against polyclonal population of NK cells.
Specificity
Recognizes human CD300a, otherwise known as IRp60 (inhibitory receptor protein 60), a 60kD transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells. Studies have shown that the cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
Reconstitution
Reconstitute with 1.0 ml distilled H2O.
Storage
Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD300A
Q9UGN4 NM_007261 CAB52291.1

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Reactivity: Human
Range: 7.8-500 pmol/ml
Reactivity: Rat
Range: 0.156-10 ng/ml
Renal tissue presenting zygomycosis stained with Mouse anti-Rhizopus Arrhizus
Species: Fungus
Applications: IHC - Paraffin, Western blot, ELISA

Requested From: United States
Date Requested: 6/25/2019
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