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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-C12543-200 200 µl $530 
Antibody

Monoclonal Mouse anti‑Human CASP8 / Caspase 8 Antibody (C‑Terminus, WB) LS‑C12543

Monoclonal Mouse anti‑Human CASP8 / Caspase 8 Antibody (C‑Terminus, WB) LS‑C12543

Antibody:
Mouse Monoclonal to Human CASP8 / Caspase 8
Application:
WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$530 
LS-C12543-200
200 µl
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Mouse Monoclonal to Human CASP8 / Caspase 8
Application:
WB, IP, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Caspase 8 antibody LS-C12543 is an unconjugated mouse monoclonal antibody to human Caspase 8 (CASP8) (C-Terminus). Validated for ELISA, IP and WB.
Target
Human CASP8 / Caspase 8
Synonyms
CASP8 | ALPS2B | Apoptotic protease Mch-5 | Apoptotic cysteine protease | Casp-8 | Caspase-8 | CAP4 | Caspase 8 | MACH | MCH5 | MORT1-associated ced-3 homolog | ICE-like apoptotic protease 5 | Pro Caspase 8 | FADD-like ICE | FLICE | MACH-alpha-1/2/3 protein | MACH-beta-1/2/3/4 protein
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • Immunoprecipitation (1:100)
  • ELISA
Immunogen
Synthetic peptide derived from the C-Terminus sequence of the p18 fragment of human caspase-8 (KLH).
Epitope
C-Terminus
Specificity
Recognizes endogenous levels of full length human caspase-8 (57kD) as well as the cleaved intermediate p43/p41 and the caspase-8 active subunit p18. This antibody does not cross-react with other caspases.
Usage
Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:1000. Immunoprecipitation: 1:100.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 0.02% Sodium Azide, 50% Glycerol
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CASP8 / Caspase 8
Q14790 nm_001228 AAC50645.1

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Requested From: United States
Date Requested: 7/16/2020