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| Catalog Number | Size | Price |
|---|---|---|
| LS-C498467-50 | 50 µg | $294 |
| LS-C498467-100 | 100 µg | $360 |
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Polyclonal Rabbit anti‑Human BUB3 Antibody (IHC, WB) LS‑C498467
Polyclonal Rabbit anti‑Human BUB3 Antibody (IHC, WB) LS‑C498467
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
BUB3 antibody LS-C498467 is an unconjugated rabbit polyclonal antibody to BUB3 from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB.
Target
Human BUB3
Synonyms
BUB3 | Budding uninhibited by benomyl | HBUB3 | BUB3L | Mitotic checkpoint component
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant human Mitotic checkpoint protein BUB3 protein (6-217AA)
Specificity
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Applications
- IHC
- Western blot
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BUB3
Publications (0)
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Featured Products
Species:
Drosophila melanogaster
Applications:
Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Flow Cytometry, Functional Assay
Reactivity:
Human
Range:
1.25-80 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 9/20/2024
Date Requested: 9/20/2024
