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Catalog Number	Size	Price
LS-C498456-50	50 µg	$294
LS-C498456-100	100 µg	$360

Polyclonal Rabbit anti‑Human BUB3 Antibody (HRP) LS‑C498456

Name: Anti-BUB3 Antibody | Rabbit anti-Human Polyclonal HRP ELISA | LSBio
Brand: Lifespan BioSciences
SKU: LS-C498456-50
Price: 294.0000 USD
Availability: InStock

Submit Review LSBio Guarantee

Antibody:

BUB3 Rabbit anti-Human Polyclonal (HRP) Antibody

Application:

ELISA

Reactivity:

Human

Format:

Horseradish Peroxidase, Unmodified

Other formats:

Biotin Unconjugated FITC

$294

LS-C498456-50

Toll Free North America

206-374-1102

For Research Use Only

Specifications Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

BUB3 Rabbit anti-Human Polyclonal (HRP) Antibody

Application:

ELISA

Reactivity:

Human

Format:

Horseradish Peroxidase, Unmodified

Other formats:

Biotin Unconjugated FITC

Specifications

Description

BUB3 antibody LS-C498456 is an HRP-conjugated rabbit polyclonal antibody to human BUB3. Validated for ELISA.

Target

Human BUB3

Synonyms

BUB3 | Budding uninhibited by benomyl | HBUB3 | BUB3L | Mitotic checkpoint component

See All BUB3 Antibodies

Host

Rabbit

Reactivity

Human (tested or 100% immunogen sequence identity)

Clonality

IgG Polyclonal

Conjugations

Horseradish Peroxidase. Also available Unconjugated or conjugated with Biotin, FITC.

Purification

Protein G purified

Modifications

Unmodified

Immunogen

Recombinant human Mitotic checkpoint protein BUB3 protein (6-217AA)

Specificity

Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.

Applications