LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
ATXN3 / JOS Antibody (aa30‑45) LS‑C3125
JOS antibody LS-C3125 is an unconjugated rabbit polyclonal antibody to JOS (ATXN3) from human, mouse, rat and other species. Validated for ELISA.
Antibody
Catalog
Size
Price
LS-C3125-100
100 µg
Unavailable

Popular ATXN3 / JOS Products

Formalin-fixed and paraffin-embedded human brain tissue reacted with ATXN3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
IHC of paraffin-embedded H661 xenograft using Ataxin 3 antibody at 1:500 dilution.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, Flow Cytometry, ELISA
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Horse, Pig, Sheep
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry of paraffin-embedded human pancreas tissue using antibody at 1: 100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

JOS antibody LS-C3125 is an unconjugated rabbit polyclonal antibody to JOS (ATXN3) from human, mouse, rat and other species. Validated for ELISA.
About ATXN3 / JOS
Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. P54252 NM_004993 NP_004984.2

ATXN3 Antibody, ATX3 Antibody, Ataxin 3 Antibody, Ataxin 3 variant h Antibody, AT3 Antibody, Ataxin 3 variant m Antibody, Ataxin 3 variant ref Antibody, Ataxin-3 Antibody, Olivopontocerebellar ataxia 3 Antibody, SCA3 Antibody, MJD1 Antibody, JOS Antibody, Josephin Antibody, MJD Antibody


Specifications

Target
Mouse ATXN3 / JOS
Host
Rabbit
Reactivity
Mouse, Human, Monkey, Rat, Bovine, Dog, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA (1:1000)
Immunogen
ATXN3 / JOS antibody was raised against synthetic peptide from mouse ATXN3 / Ataxin-3. Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Mouse, Rat, Panda, Dog, Bovine, Horse, Rabbit, Pig, Platypus (100%).
Epitope
aa30-45
Specificity
KLH conjugated synthetic peptide comprising amino acids 30 - 45 [PVELSSIAHQLDEEER] of the mouse Machado-Joseph disease (Mjd) protein.
Presentation
PBS, 0.09% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Requested From: 
Date Requested: 7/15/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number