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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ATXN3 / JOS Antibody (aa120‑250) LS‑C348291
JOS antibody LS-C348291 is an unconjugated goat polyclonal antibody to JOS (ATXN3) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C348291-200
200 µl (3 mg/ml)
$355

Popular ATXN3 / JOS Products

Formalin-fixed and paraffin-embedded human brain tissue reacted with ATXN3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
IHC of paraffin-embedded H661 xenograft using Ataxin 3 antibody at 1:500 dilution.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, Flow Cytometry, ELISA
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Horse, Pig, Sheep
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry of paraffin-embedded human pancreas tissue using antibody at 1: 100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, ELISA

Product Description

JOS antibody LS-C348291 is an unconjugated goat polyclonal antibody to JOS (ATXN3) from human, mouse, rat and other species. Validated for WB.
About ATXN3 / JOS
Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. P54252 NM_004993 NP_004984.2

ATXN3 Antibody, ATX3 Antibody, Ataxin 3 Antibody, Ataxin 3 variant h Antibody, AT3 Antibody, Ataxin 3 variant m Antibody, Ataxin 3 variant ref Antibody, Ataxin-3 Antibody, Olivopontocerebellar ataxia 3 Antibody, SCA3 Antibody, MJD1 Antibody, JOS Antibody, Josephin Antibody, MJD Antibody


Specifications

Target
Human ATXN3 / JOS
Host
Goat
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Cat, Dog, Goat, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Donkey (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:250 - 1:2000)
Immunogen
ATXN3 / JOS antibody was raised against purified recombinant peptide derived from within residues 120 aa of 250 aa of human ATXN3 produced in E. coli.
Epitope
aa120-250
Specificity
Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot.
Presentation
PBS, 0.05% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images

Western blot

Anti-ATXN3 antibody at 1:500 dilution. Lysates at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.
Anti-ATXN3 antibody at 1:500 dilution. Lysates at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.

Western blot

Anti-ATXN3 antibody at 1:500 dilution. Lysates at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.
Anti-ATXN3 antibody at 1:500 dilution. Lysates at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.

Western blot

Anti-ATXN3 antibody at 1:500 dilution. Lysates at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.
Anti-ATXN3 antibody at 1:500 dilution. Lysates at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.

Western blot

Anti-ATXN3 antibody at 1:500 dilution. Lysates at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.
Anti-ATXN3 antibody at 1:500 dilution. Lysates at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.

Requested From: United States
Date Requested: 7/20/2018

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