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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ATXN3 / JOS

ataxin 3

Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. Binds long polyubiquitin chains and trims them, while it has weak or no activity against chains of 4 or less ubiquitins. Involved in degradation of misfolded chaperone substrates via its interaction with STUB1/CHIP: recruited to monoubiquitinated STUB1/CHIP, and restricts the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. In response to misfolded substrate ubiquitination, mediates deubiquitination of monoubiquitinated STUB1/CHIP. Interacts with key regulators of transcription and represses transcription: acts as a histone-binding protein that regulates transcription.

Gene Name: ataxin 3
Synonyms: ATXN3, ATX3, Ataxin 3, Ataxin 3 variant h, AT3, Ataxin 3 variant m, Ataxin 3 variant ref, Ataxin-3, Olivopontocerebellar ataxia 3, SCA3, MJD1, JOS, Josephin, MJD
Target Sequences: NM_004993 NP_004984.2 P54252

Viewing 1-25 of 38 items
ATXN3 / JOS Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Human ATXN3 / JOS
Mouse, Sheep, Bovine, Rat, Pig, Horse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
ATXN3 / JOS Antibody - IHC of paraffin-embedded H661 xenograft using Ataxin 3 antibody at 1:500 dilution.
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Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100µl   0.98mg/ml   $355.00
ATXN3 / JOS Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
ATXN3 / JOS Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50µg   $285.00; 100µg   $385.00
ATXN3 / JOS Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
ATXN3 / JOS Antibody - Immunohistochemistry of paraffin-embedded human lung cancer using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50µg   $285.00; 100µg   $385.00
ATXN3 / JOS Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with ATXN3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Rabbit Polyclonal to Human ATXN3 / JOS
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
ATXN3 / JOS Antibody - Immunofluorescence analysis of HeLa cells.
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Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl   $650.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl   $650.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl   $650.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
ATXN3 / JOS Antibody - Ataxin 3 antibody IHC-paraffin. IHC(P): Human Lung Cancer Tissue.
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Rabbit Polyclonal to Human ATXN3 / JOS
Dog, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   $325.00
ATXN3 / JOS Antibody
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
ATXN3 / JOS Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Select
Rabbit Polyclonal to Human ATXN3 / JOS
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
ATXN3 / JOS Antibody - ATXN3 / JOS antibody. IHC(P): Human Lung Cancer Tissue.
Select
Rabbit Polyclonal to Human ATXN3 / JOS
Xenopus, Rat, Pig, Horse, Mouse, Sheep, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µg   200µl   0.5mg/ml   $305.00
ATXN3 / JOS Antibody
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   $435.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Mouse, Human
IF, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human ATXN3 / JOS
Human
IF, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00

Viewing 1-25 of 38 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).