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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ZAP70 Antibody (aa280‑309, FITC) LS‑C132976
Antibody
ZAP70 antibody LS-C132976 is an FITC-conjugated mouse monoclonal antibody to human ZAP70. Validated for Flow.
Catalog
Size
Price
LS-C132976-100
100 µg
Unavailable

Popular ZAP70 Products

IHC of paraffin-embedded human lymph showing cytoplasmic localization using ZAP70 antibody with DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Formalin-Fixed, paraffin-embedded human tonsil stained with peroxidase-conjugate and AEC chromogen. Note staining of T-Cells.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
IHC of paraffin-embedded human breast carcinoma, using ZAP-70 (Phospho-Tyr493) Antibody. The picture on the right is treated with the synthesized peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-ZAP70 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7841 dilution 1:200.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Western blot of recombinant ZAP70.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: Western blot

Product Description

ZAP70 antibody LS-C132976 is an FITC-conjugated mouse monoclonal antibody to human ZAP70. Validated for Flow.
About ZAP70
Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Contributes also to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the doubly phosphorylated TCR component CD247/CD3Z through ITAM motif at the plasma membrane. P43403 NM_207519 P43403

ZAP70 Antibody, 70 kDa zeta-associated protein Antibody, SRK Antibody, STCD Antibody, STD Antibody, Syk-related tyrosine kinase Antibody, Tyrosine-protein kinase ZAP-70 Antibody, TZK Antibody, ZAP-70 Antibody, Zeta-associated protein 70 Antibody


Specifications

Target
Human ZAP70
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Fluorescein. Also available conjugated with FITC, AP, Biotin, PE, FITC, PE.
Purification
Purified
Modifications
Unmodified
Applications
  • Flow Cytometry
  • (applications tested for the base form of this product only)
Immunogen
ZAP70 antibody was raised against peptide corresponding to aa280-309 of human ZAP-70 (KLH).
Epitope
aa280-309
Specificity
Recognizes human ZAP-70 at ~70kD.
Usage
Suitable for use in Flow cytometry: 10 ul labels 10^6 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% sodium azide
Storage
Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze-thaw cycles. Protect from light.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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