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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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VR1 / TRPV1 Antibody (DY550) LS‑C181942
Antibody
TRPV1 antibody LS-C181942 is a DY550-conjugated rabbit polyclonal antibody to TRPV1 (VR1) from human, mouse, rat and other species. Validated for ICC, IF and WB.
Catalog
Size
Price
LS-C181942-100
100 µl (1.3 mg/ml)
Unavailable

Popular VR1 / TRPV1 Products

Anti-TRPV1 antibody LS-A9670 IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Species: Human, Mouse, Rat, Primate
Applications: ICC, Immunofluorescence, Western blot
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

TRPV1 antibody LS-C181942 is a DY550-conjugated rabbit polyclonal antibody to TRPV1 (VR1) from human, mouse, rat and other species. Validated for ICC, IF and WB.
About VR1 / TRPV1
Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Q8NER1 NM_018727 NP_061197.4

TRPV1 Antibody, Capsaicin receptor Antibody, OTRPC1 Antibody, Vanilloid receptor subtype 1 Antibody, Osm-9-like TRP channel 1 Antibody, Vanilloid receptor 1 Antibody, VR1 Antibody


Specifications

Target
Rat VR1 / TRPV1
Host
Rabbit
Reactivity
Rat, Human, Mouse, Primate (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
DyLight 550. Also available Unconjugated or conjugated with Biotin, DY650, DY488.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • ICC (1:40)
  • Immunofluorescence
  • Western blot (1:1000)
  • (applications tested for the base form of this product only)
Failed Applications
  • IHC
Immunogen
VR1 / TRPV1 antibody was raised against a synthetic peptide made to an N-terminal portion of the rat TRPV1 protein (between residues 1-50) [UniProt O35433].
Specificity
In Western Blot, a band is seen ~100 kDa representing TRPV1. In ICC/IF, plasma membrane staining is observed in Ntera-2 cells.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at 4°C in the dark.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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