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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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VR1 / TRPV1

transient receptor potential cation channel, subfamily V, member 1

Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity). Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca2+-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel.

Gene Name: transient receptor potential cation channel, subfamily V, member 1
Family/Subfamily: Ion Channel , Calcium channel - TRP
Synonyms: TRPV1, Capsaicin receptor, OTRPC1, Vanilloid receptor subtype 1, Osm-9-like TRP channel 1, Vanilloid receptor 1, VR1
Target Sequences: NM_018727 NP_061197.4 Q8NER1

Filtered by: None
Target
VR1 / TRPV1 (55)
Reactivity
Human (46)
Mouse (20)
Rat (22)
Guinea pig (9)
Monkey (1)
Primate (5)
Application
IHC (38)
IHC-Fr (3)
IHC-P (13)
WB (28)
ELISA (11)
ICC (13)
IF (10)
IP (2)
Host
rabbit (52)
mouse (1)
guinea pig (2)
Isotype
IgG (17)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (54)
Clone
1A8 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (3)
Magnetic beads Conjugated (1)
PE Conjugated (2)
Sepharose Conjugated (1)
Unconjugated (27)
Epitope
aa1-153 (10)
Internal (7)
C-Terminus (6)
N-Terminus (5)
aa105-115 (1)
aa124-153 (1)
aa531-541 (1)
aa608-621 (1)
aa817-838 (1)
Publications
No (55)
Showing 1-25 of 55 results

VR1 / TRPV1 Antibody (Internal) IHC-plus™ LS-A9670
Rabbit Polyclonal to Human VR1 / TRPV1
Guinea pig, Human
IHC IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-TRPV1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

VR1 / TRPV1 Antibody (Internal, FITC) IHC-plus™ LS-A109796
Rabbit Polyclonal to Human VR1 / TRPV1
Guinea pig, Human
IHC IHC-P
FITC Conjugated
100µl  $650.00
Anti-TRPV1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

VR1 / TRPV1 Antibody (Internal, Azide-free, HRP) IHC-plus™ LS-A109797
Rabbit Polyclonal to Human VR1 / TRPV1
Guinea pig, Human
IHC IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-TRPV1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

VR1 / TRPV1 Antibody IHC-plus™ LS-B12677
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Human
ICC IHC IHC-P
Unconjugated
100µl 0.5mg/ml  $425.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

VR1 / TRPV1 Antibody (Biotin) LS-C180117
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Human
ICC IHC IHC-P
Biotin Conjugated
100µl 1.03mg/ml  $365.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

VR1 / TRPV1 Antibody (DY650) LS-C180118
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Human
ICC IHC IHC-P
DY650 Conjugated
100µl 1.03mg/ml  $365.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

VR1 / TRPV1 Antibody (DY550) LS-C180121
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Human
ICC IHC IHC-P
DY550 Conjugated
100µl 1.03mg/ml  $365.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

VR1 / TRPV1 Antibody (DY488) LS-C180119
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Human
ICC IHC IHC-P
DY488 Conjugated
100µl 1.03mg/ml  $365.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

VR1 / TRPV1 Antibody LS-C150735
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Rat, Primate, Human
ICC IF WB
Unconjugated
100µl 1.3mg/ml  $335.00

VR1 / TRPV1 Antibody (Biotin) LS-C181938
Rabbit Polyclonal to Rat VR1 / TRPV1
Mouse, Rat, Primate, Human
ICC IF WB
Biotin Conjugated
100µl 0.9mg/ml  $365.00

VR1 / TRPV1 Antibody (N-Terminus) LS-C172124
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Rat, Human
IHC WB
Unconjugated
100µg 1mg/ml  $295.00
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

VR1 / TRPV1 Antibody (N-Terminus, Magnetic beads) LS-C172125
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Rat, Human
IHC IP WB
Magnetic beads Conjugated
100µg 1mg/ml  $325.00
 This image was taken for the unconjugated form of this product. Other forms have not been tested.
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

VR1 / TRPV1 Antibody (clone 1A8) LS-C139103
Mouse Monoclonal [clone 1A8] (IgG2a,k) to Human VR1 / TRPV1
Rat, Human
ELISA WB
Unconjugated
100µg  $355.00
TRPV1 monoclonal antibody (M02), clone 1A8. Western blot of TRPV1 expression in rat thymus.
Detection limit for recombinant GST tagged TRPV1 is 0.03 ng/ml as a capture antibody.

VR1 / TRPV1 Antibody (N-Terminus) LS-C21203
Rabbit Polyclonal (IgG) to Rat VR1 / TRPV1
Rat
ICC IF IHC WB
Unconjugated
50µl  $455.00

VR1 / TRPV1 Antibody (aa124-153) LS-C160237
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
TRPV1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
TRPV1 Antibody western blot of A549 cell line lysates (35 ug/lane). The TRPV1 antibody detected the TRPV1 protein (arrow).

VR1 / TRPV1 Antibody (C-Terminus) LS-C21195
Rabbit Polyclonal (IgG) to Rat VR1 / TRPV1
Rat
ELISA IHC WB
Unconjugated
50µg 50µl 1mg/ml  $445.00; 100µg  $755.00

VR1 / TRPV1 Antibody (aa531-541) LS-C77694
Rabbit Polyclonal to Mouse VR1 / TRPV1
Mouse, Guinea pig, Human, Monkey
IHC
Unconjugated
100µl  $590.00

VR1 / TRPV1 Antibody (aa608-621) LS-C77695
Rabbit Polyclonal to Human VR1 / TRPV1
Guinea pig, Human
IHC
Unconjugated
100µl  $590.00

VR1 / TRPV1 Antibody (N-Terminus) LS-C353806
Rabbit Polyclonal to Human VR1 / TRPV1
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of TRPV1 expression in HeLa (A); Raw264.7 (B); PC12 (C) whole cell lysates.

VR1 / TRPV1 Antibody LS-C501373
Rabbit Polyclonal (IgG) to Human VR1 / TRPV1
Human
ELISA IF IHC
Unconjugated
50µg  $285.00; 100µg 5mg/ml  $385.00
Immunohistochemistry of paraffin-embedded human colon cancer using TRPV1 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using TRPV1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

VR1 / TRPV1 Antibody LS-C21197
Rabbit Polyclonal (IgG) to Mouse VR1 / TRPV1
Mouse
IHC
Unconjugated
50µl  $435.00; 100µl  $635.00

VR1 / TRPV1 Antibody (aa1-153, Biotin) LS-C423974
Rabbit Polyclonal to Human VR1 / TRPV1
Human
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00

VR1 / TRPV1 Antibody (aa1-153, PE) LS-C727549
Rabbit Polyclonal to Human VR1 / TRPV1
Human
IHC WB
PE Conjugated
100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Human Kidney.
Western blot of VR1 / TRPV1 antibody using recombinant TRPV1.

VR1 / TRPV1 Antibody (aa817-838) LS-C21202
Guinea pig Polyclonal (IgG) to Rat VR1 / TRPV1
Rat
IHC
Unconjugated
50µl  $455.00

VR1 / TRPV1 Antibody LS-C355619
Rabbit Polyclonal (IgG) to Human VR1 / TRPV1
Human
IF IHC IHC-Fr
Unconjugated
100µg  $425.00
IHC using Vanilloid Receptor 1 Antibody
IHC using Vanilloid Receptor 1 Antibody
Showing 1-25 of 55 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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