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VR1 / TRPV1 Antibody (C‑Terminus) LS‑C21195
TRPV1 antibody LS-C21195 is an unconjugated rabbit polyclonal antibody to rat TRPV1 (VR1). Validated for ELISA, IHC and WB.
Antibody
Catalog
Size
Price
LS-C21195-50
50 µg (1 mg/ml)
Unavailable
LS-C21195-100
100 µg
Unavailable

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Product Description

TRPV1 antibody LS-C21195 is an unconjugated rabbit polyclonal antibody to rat TRPV1 (VR1). Validated for ELISA, IHC and WB.
About VR1 / TRPV1
Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Q8NER1 NM_018727 NP_061197.4

TRPV1 Antibody, Capsaicin receptor Antibody, OTRPC1 Antibody, Vanilloid receptor subtype 1 Antibody, Osm-9-like TRP channel 1 Antibody, Vanilloid receptor 1 Antibody, VR1 Antibody


Specifications

Target
Rat VR1 / TRPV1
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Predicted
Guinea pig (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1 - 20 µg/ml)
  • Western blot (1 - 10 µg/ml)
  • ELISA (0.5 - 1 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
VR1 / TRPV1 antibody was raised against a 15 amino acid peptide corresponding to the C-terminus of the rat Capsaicin Receptor protein (KLH coupled).
Epitope
C-Terminus
Specificity
Recognizes rat Capsaicin Receptor (Vanilloid Receptor 1, VR1). No significant sequence homology with VRL-1 or TRP or other proteins. Species sequence homology: guinea pig (93%); human (66%).
Usage
Suitable for use in Western Blot, IHC, and ELISA. Western Blot: 1-10 ug/ml using ECL. ELISA: 0.5-1 ug/ml. Control peptide can be used to coat ELISA plates at 1 ug/ml. IHC: Paraformaldehyde fixedsections.
Presentation
Tris, pH 7.5, 0.2% BSA, 0.05% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 7/19/2018

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