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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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URI1 / NNX3 Antibody (aa359‑408) LS‑C111293
NNX3 antibody LS-C111293 is an unconjugated rabbit polyclonal antibody to NNX3 (URI1) from human, horse, monkey and other species. Validated for WB.
Catalog
Size
Price
LS-C111293-50
50 µg (1 mg/ml)
Unavailable

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Product Description

NNX3 antibody LS-C111293 is an unconjugated rabbit polyclonal antibody to NNX3 (URI1) from human, horse, monkey and other species. Validated for WB.
About URI1 / NNX3
Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. O94763 NM_003796 NP_003787.2

URI1 Antibody, C19orf2 Antibody, NNX3 Antibody, PPP1R19 Antibody, RMP Antibody, RPB5-mediating protein Antibody, URI Antibody, Protein NNX3 Antibody, URI1, prefoldin-like chaperone Antibody


Specifications

Target
Human URI1 / NNX3
Host
Rabbit
Reactivity
Human, Monkey, Horse, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Bovine, Guinea pig, Chicken (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
URI1 / NNX3 antibody was raised against synthetic peptide located between aa359-408 of human URI1 (Q6NX55). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Elephant, Rabbit (100%); Bovine, Guinea pig, Chicken, Platypus (92%); Galago, Horse, Opossum, Xenopus (85%); Mouse (78%).
Epitope
aa359-408
Specificity
Human C19orf2 / NNX3
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
50 µl Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

C19orf2 / NNX3 antibody LS-C111293 Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
C19orf2 / NNX3 antibody LS-C111293 Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

C19orf2 / NNX3 antibody LS-C111293 Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
C19orf2 / NNX3 antibody LS-C111293 Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

C19orf2 / NNX3 antibody LS-C111293 Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
C19orf2 / NNX3 antibody LS-C111293 Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

C19orf2 / NNX3 antibody LS-C111293 Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
C19orf2 / NNX3 antibody LS-C111293 Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/18/2018

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